1. Bluetongue Disease, that was recently seen in news, is transmitted by which species?
[A] Bat
[B] Culicoides midges
[C] Houseflies
[D] Spider
Show Answer
Correct Answer: B [Culicoides midges]
Notes:
Bluetongue Virus (BTV) has recently been detected in more suspected cases in Northern Ireland, raising concerns about livestock health. Bluetongue is a severe haemorrhagic disease that affects animals and is infectious, but it is non-contagious and spreads only through insect vectors. The virus mainly infects domestic ruminants such as cattle, sheep, and goats, as well as wild animals like buffalo, deer, antelope, and camels, with sheep being the most severely affected. It spreads primarily through the bites of infected Culicoides midges, which are tiny blood-feeding insects commonly found on farms. There is no effective treatment for bluetongue, but vaccines are available for certain strains and are used in Africa, Asia, and parts of Europe.
2. Which institute has developed GlowCas9, a CRISPR protein that glows during gene editing?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Bose Institute, Kolkata
[C] National Centre for Biological Sciences (NCBS), Bengaluru
[D] Council of Scientific and Industrial Research (CSIR)
Show Answer
Correct Answer: B [Bose Institute, Kolkata]
Notes:
Scientists at the Bose Institute, Kolkata have developed GlowCas9, a CRISPR protein that glows during gene editing. It is a bioluminescent Cas9, created by fusing Cas9 with a split nano-luciferase enzyme from deep-sea shrimp proteins. GlowCas9 is highly stable, retaining structure and activity even at higher temperatures. When Cas9 folds correctly, the luciferase pieces reconnect and produce light, enabling real-time, non-harmful tracking of gene editing in cells, tissues, and plant leaves. It improves the precision of Homology-Directed Repair (HDR), a key DNA repair process for genetic diseases like sickle cell anaemia and muscular dystrophy. GlowCas9 advances theratracking, the visual monitoring of molecular gene therapy in action.
3. What is the name of the Chandrayaan-3 lander payload that detected the active plasma environment at the Moon’s south pole?
[A] RAMBHA-LP
[B] ChaSTE
[C] ILSA (Instrument for Lunar Seismic Activity)
[D] LRA (LASER Retroreflector Array)
Show Answer
Correct Answer: A [RAMBHA-LP]
Notes:
Chandrayaan-3’s lander payload RAMBHA-LP (Radio Anatomy of Moon Bound Hypersensitive Ionosphere and Atmosphere – Langmuir Probe) detected an active plasma environment in the Moon’s south polar region. Plasma, the 4th state of matter, is electrically neutral and contains charged particles like ions and free electrons. RAMBHA-LP uses a hypersensitive Langmuir probe mounted on a boom to avoid interference from the lander. It measures electron density and electron temperature near the lunar surface, helping understand the plasma behaviour at the Moon’s South Pole.
4. India launched its first hydrogen-powered water taxi service in which city?
[A] Kolkata
[B] Prayagraj
[C] Chennai
[D] Varanasi
Show Answer
Correct Answer: D [Varanasi]
Notes:
India launched its first hydrogen-powered water taxi service in Varanasi on December 10, 2025. The service was inaugurated by Union Minister of Ports, Shipping & Waterways Sarbananda Sonowal, marking a major advancement in India’s clean transport initiatives. The water taxi has been built by Cochin Shipyard, integrating modern engineering with sustainability. It operates on a hybrid electric–hydrogen propulsion system, ensuring zero emissions, low noise levels and high environmental safety. The vessel is equipped with five hydrogen cylinders and 3 kW solar panels, which help meet auxiliary power needs.
5. Which institute has developed a nanoparticle-based therapy for Alzheimer’s Disease (AD)?
[A] Institute of Nano Science and Technology (INST), Mohali
[B] Indian Institute of Technology, Delhi
[C] All India Institute of Medical Sciences, New Delhi
[D] Council of Scientific and Industrial Research – National Chemical Laboratory, Pune
Show Answer
Correct Answer: A [Institute of Nano Science and Technology (INST), Mohali]
Notes:
Researchers at the Institute of Nano Science and Technology (INST), Mohali, developed a new nanoparticle-based therapy for Alzheimer’s Disease (AD). Conventional AD therapies target only one feature like amyloid aggregation or oxidative stress, giving limited benefit. The new therapy uses nanoparticles integrating polyphenol (from green tea), dopamine (a neurotransmitter), and tryptophan (an amino acid). These form EGCG-dopamine-tryptophan nanoparticles (EDTNPs) targeting amyloid aggregation, oxidative stress, inflammation, and neuronal degeneration simultaneously.
6. Antariksh Prayogshala (Space Labs) is an initiative of which organization?
[A] Indian Space Research Organisation
[B] Indian National Space Promotion and Authorisation Centre
[C] Defence Research and Development Organisation
[D] Ministry of Finance
Show Answer
Correct Answer: B [Indian National Space Promotion and Authorisation Centre]
Notes:
Indian National Space Promotion and Authorisation Centre (IN-SPACe) issued a Request for Proposal (RfP) to set up Antariksh Prayogshala (Space Labs) in select academic institutions. It is a first-of-its-kind IN-SPACe initiative to build advanced space labs inside Indian colleges and universities. Labs will give hands-on training to students in space technology across the country. IN-SPACe will fund 75% of project cost, capped at ₹5 crore per institution, released based on milestones.
7. India’s first indigenous Magnetic Resonance Imaging (MRI) scanner developed by VoxelGrids was deployed in which state?
[A] Maharashtra
[B] Gujarat
[C] Uttar Pradesh
[D] Madhya Pradesh
Show Answer
Correct Answer: A [Maharashtra]
Notes:
VoxelGrids, a Zoho-backed Indian start-up, has developed India’s first indigenous Magnetic Resonance Imaging (MRI) scanner, marking a major milestone for Made-in-India medical technology. The MRI scanner has been deployed at Chandrapur Cancer Care Foundation near Nagpur, Maharashtra, after a 12-year development effort led by founder Arjun Arunachalam. It does not use liquid helium, making it around 40% cheaper to build and significantly reducing operating and power costs. VoxelGrids offers a pay-per-use model, helping smaller hospitals afford MRI services without high upfront costs.
8. India has inaugurated the world’s second National Environmental Standard Laboratory (NESL) in which city?
[A] Bengaluru
[B] New Delhi
[C] Chennai
[D] Hyderabad
Show Answer
Correct Answer: B [New Delhi]
Notes:
India inaugurated the world’s second National Environmental Standard Laboratory (NESL) and the world’s fifth National Primary Standard Facility for Solar Cell Calibration at CSIR–National Physical Laboratory (NPL), New Delhi. NESL will provide India-specific calibration and certification of air pollution monitoring systems, supporting regulatory bodies, industries, and startups, and improving policy enforcement under programmes like the National Clean Air Programme (NCAP).
9. Which telescope of NASA recently discovered a new astronomical object named Cloud-9?
[A] Spitzer Space Telescope
[B] Roman Space Telescope
[C] Hubble Space Telescope
[D] James Webb Space Telescope
Show Answer
Correct Answer: C [Hubble Space Telescope]
Notes:
NASA’s Hubble Space Telescope discovered a new astronomical object named Cloud-9. Cloud-9 is a starless, gas-rich, dark-matter-dominated cloud, classified as a Reionization-Limited H I Cloud (RELHIC). It is located 14 million light-years from Earth, near the spiral galaxy Messier 94 (M94). The cloud is made of neutral hydrogen (H I) spanning about 4,900 light-years, with a mass approx 1 million times the Sun. Cloud-9’s dark matter mass is estimated at 5 billion solar masses. It is a relic of early galaxy formation, a “failed galaxy” that did not form stars.
10. What is ‘Orobanche aegyptiaca’ that was recently seen in news?
[A] Newly discovered species of fish
[B] Parasitic flowering weed
[C] Traditional medicine
[D] None of the Above
Show Answer
Correct Answer: B [Parasitic flowering weed]
Notes:
India’s largest oilseed crop, mustard, is under threat from the parasitic weed Orobanche aegyptiaca in Rajasthan and Haryana. Orobanche aegyptiaca, locally called Margoja, is a root-parasitic flowering weed that extracts water, carbon, and nutrients from crops, causing severe yield loss. It is native to the Mediterranean–West Asian region and has spread to South Asia, North Africa, and parts of Europe. The weed thrives in north-western India and its seeds remain viable in soil for up to 20 years. It spreads via wind, irrigation, farm tools, and contaminated soil.