1. Lyme disease, that was recently seen in news, is caused by which agent?
[A] Fungus
[B] Bacteria
[C] Virus
[D] Protozoa
Show Answer
Correct Answer: B [Bacteria]
Notes:
Scientists have identified the enzyme lactate dehydrogenase (BbLDH) as essential for the survival and infectivity of Borrelia burgdorferi, the bacterium responsible for Lyme disease. Lyme disease is caused by Bacteria Borrelia burgdorferi and can affect the skin, heart, brain, and joints. It is transmitted exclusively through the bite of infected deer ticks (black-legged ticks) and cannot spread via human contact, pets, air, food, water, or insect vectors such as mosquitoes and fleas. The disease is prevalent in wooded and grassy regions, particularly in North America, Europe, and parts of Asia, with higher incidence during warmer months.
2. India has developed its first indigenous Magnetic Resonance Imaging (MRI) machine to be installed at which institute?
[A] All India Institute of Medical Sciences, New Delhi
[B] Madras Medical College
[C] All India Institute of Medical Sciences, Bhubaneswar
[D] All India Institute of Medical Sciences, Bhopal
Show Answer
Correct Answer: A [All India Institute of Medical Sciences, New Delhi]
Notes:
India has developed its first indigenous MRI machine to reduce import dependence and treatment costs. It will be installed at AIIMS Delhi by October for trials. Currently, 80-85% of medical equipment in India is imported. The indigenous MRI machine aims to boost India’s self-reliance in medical technology. An MoU was signed between AIIMS Delhi and SAMEER, an autonomous R&D lab under the Department of Electronics. The installation will be for a 1.5 Tesla MRI scanner.
3. What is “Coeliac Disease” that was recently seen in news?
[A] Viral Disease
[B] Neurological disorder
[C] Inherited autoimmune disorder
[D] Cardiovascular disease
Show Answer
Correct Answer: C [Inherited autoimmune disorder]
Notes:
Artificial Intelligence (AI) could help speed up the diagnosis of Coeliac Disease, an inherited autoimmune disorder. It is caused by an immune reaction to gluten, a protein found in wheat, barley, and rye. Eating gluten triggers intestinal damage, leading to malabsorption of nutrients. Symptoms include diarrhea, fatigue, weight loss, bloating, and anemia. In children, it can affect growth and development. 1 in 10 people with a first-degree relative having the disease are at risk. 1 in 100 people worldwide are affected. The only treatment is a strict gluten-free diet.
4. What is “Xenotransplantation” that was recently mentioned in news?
[A] Transplantation of animal organs into humans
[B] Cloning of human organs for medical use
[C] Transplantation of human organs within different individuals
[D] Use of artificial organs in humans
Show Answer
Correct Answer: A [Transplantation of animal organs into humans]
Notes:
Researchers in China successfully transplanted a gene-modified pig liver into a human with brain death to evaluate its function. Xenotransplantation involves transplanting cells, tissues, or organs from non-human animals into humans. Early attempts at xenotransplantation began in the 1980s with heart transplants. Genetic modifications are necessary to prevent immune rejection of animal organs in humans. Post-transplant monitoring is essential to assess organ function and immune responses.
5. Which institute has developed the bacteria-based technique to repair lunar bricks?
[A] Indian Institute of Science (IISc)
[B] Indian Institute of Technology (IIT) Delhi
[C] Bhabha Atomic Research Centre (BARC)
[D] None of the Above
Show Answer
Correct Answer: A [Indian Institute of Science (IISc)]
Notes:
Researchers at the Indian Institute of Science (IISc) have developed a bacteria-based technique to repair bricks for lunar habitats. Future lunar missions, like NASA’s Artemis programme, aim to establish permanent settlements on the Moon. Instead of transporting materials from Earth, astronauts will use lunar soil, or regolith, to build structures. IISc developed a method using the bacterium Sporosarcina pasteurii to create bricks from lunar and Martian soil simulants. The bacterium converts urea and calcium into calcium carbonate crystals, binding soil particles with guar gum. This method is eco-friendly and cost-effective compared to cement.
6. A huge anticyclonic storm known as the Great Red Spot is associated with which planet?
[A] Jupiter
[B] Mars
[C] Saturn
[D] Mercury
Show Answer
Correct Answer: A [Jupiter]
Notes:
New observations of the Great Red Spot on Jupiter show unexpected atmospheric activity above and around the storm. The Great Red Spot is an anticyclone, a high-pressure system that creates a long-lasting storm. It is located in Jupiter’s Southern Hemisphere. It appears as a massive red spot, though the cause of its red color remains unknown. The storm extends above Jupiter’s main cloud layers and is the largest known storm in the Solar System. The storm has existed for at least 150 years and may be even older. Its long duration is linked to Jupiter’s gaseous composition, which lacks a solid surface that would dissipate the storm’s energy. Unlike hurricanes on Earth that weaken upon landfall, Jupiter’s storm remains active due to its deep atmosphere.
7. Which Indian astronaut has been selected for the Axiom-4 mission to the International Space Station (ISS)?
[A] Ajit Krishnan
[B] Shubhanshu Shukla
[C] Angad Pratap
[D] Balakrishnan Nair
Show Answer
Correct Answer: B [Shubhanshu Shukla]
Notes:
Group Captain Shubhanshu Shukla, an Indian astronaut, will pilot the Axiom Mission 4 (Ax-4) to the International Space Station (ISS), marking a milestone for India in global space missions. Axiom Space, a private company in Houston, is organizing Ax-4 in collaboration with Indian Space Research Organisation (ISRO), European Space Agency (ESA), Poland, and Hungary. The mission crew includes Peggy Whitson (commander), Sławosz Uznański-Wiśniewski from Poland, and Tibor Kapu from Hungary. The team will stay for 14 days aboard the ISS and carry out around 60 scientific experiments, highlighting international cooperation in space exploration.
8. According to recent study in Madagascar, which species was identified as the exclusive carrier of the Hantavirus?
[A] Black rat
[B] Fruit bat
[C] Mosquitofish
[D] Bull frog
Show Answer
Correct Answer: A [Black rat]
Notes:
A study in Madagascar found that hantavirus is carried only by black rats, also called Rattus rattus, in rural areas. These rats came from Asia and were introduced to Madagascar between the 10th and 14th centuries, spreading widely since then. Researchers tested around 2,000 animals, but no native rodents, bats, or other small animals had the virus. Hantavirus is a rare but deadly virus spread by infected rodents. It transmits through contact with rodent urine, feces, or saliva, mainly through air particles or direct contact. Human-to-human spread is extremely rare, so environmental exposure is the key risk.
9. What type of disease is Signet Ring Cell Carcinoma (SRCC) that was recently seen in news?
[A] Rare and aggressive subtype of colorectal cancer
[B] Neurodegenerative disorder
[C] Cardiovascular disease
[D] Autoimmune disease
Show Answer
Correct Answer: A [Rare and aggressive subtype of colorectal cancer]
Notes:
Indian scientists have developed new ways to study and treat Signet Ring Cell Carcinoma (SRCC), a rare and aggressive form of Colorectal Cancer (CRC). Signet Ring Cell Carcinoma (SRCC) starts in the colon or rectum and gets its name from its ring-shaped cells, where mucus pushes the nucleus to one side. It spreads quickly, resists treatment, and is often detected late, making it deadly. Researchers created Patient-Derived Organoids (PDOs), which are 3D tumour models, and Patient-Derived Xenografts (PDXs), where tumour cells are grown in mice. These models mimic real tumours and help test treatments. Though SRCC is rare globally, in India, cases are almost 10 times higher, often affecting younger people.
10. NISAR is a joint Earth observation satellite mission developed by which two space agencies?
[A] National Aeronautics and Space Administration (NASA) and Indian Space Research Organisation (ISRO)
[B] European Space Agency (ESA) and Japan Aerospace Exploration Agency (JAXA)
[C] Indian Space Research Organisation (ISRO) and China National Space Administration (CNSA)
[D] European Space Agency (ESA) and China National Space Administration (CNSA)
Show Answer
Correct Answer: A [National Aeronautics and Space Administration (NASA) and Indian Space Research Organisation (ISRO)]
Notes:
NISAR (NASA-ISRO Synthetic Aperture Radar) is a joint satellite mission by the National Aeronautics and Space Administration (NASA) and the Indian Space Research Organisation (ISRO). It is set to be launched in June 2025 from the Satish Dhawan Space Centre in Andhra Pradesh using the Geosynchronous Satellite Launch Vehicle Mark II (GSLV Mk II). This is the first radar-based Earth observation mission jointly developed by India and the United States. NISAR will map the entire Earth’s surface every 12 days to provide frequent and accurate data. It will track ecosystem changes, ice movements, vegetation shifts, sea level rise, groundwater levels, and natural disasters like earthquakes, volcanoes, tsunamis, and landslides.