1. Which two countries jointly announced the discovery of a new subtype of Maturity-Onset Diabetes of the Young (MODY) in May 2025?
[A] India and China
[B] India and the United States of America (USA)
[C] India and France
[D] Russia and China
Show Answer
Correct Answer: B [India and the United States of America (USA)]
Notes:
Indian and US researchers have recently discovered a new subtype of Maturity-Onset Diabetes of the Young (MODY), a rare, inherited form of diabetes. MODY is caused by genetic mutations that lead to impaired insulin production or function. It is typically diagnosed in adolescents or young adults under 35 years of age, without significant obesity. The discovery was made by researchers from the Madras Diabetes Research Foundation (MDRF) in Chennai and Washington University School of Medicine in St. Louis. This breakthrough could change the way certain forms of MODY are diagnosed and treated, offering better solutions for patients. MODY is divided into 14 subtypes, each linked to different gene mutations.
2. Which institution has developed the LICONN technology to map brain cell connections using light microscopes?
[A] Institute of Science and Technology Austria (ISTA)
[B] Massachusetts Institute of Technology (MIT)
[C] All India Institute Of Medical Sciences (AIIMS) Delhi
[D] None of the Above
Show Answer
Correct Answer: A [Institute of Science and Technology Austria (ISTA)]
Notes:
Scientists recently developed a new technique called Light-microscopy-based Connectomics (LICONN) to map brain cell connections using light microscopes. LICONN was developed at the Institute of Science and Technology Austria (ISTA). It allows mapping of brain’s complex neural networks at the nanoscale and also identifies specific molecules in those connections. LICONN combines light microscopy with hydrogel expansion, fluorescent stains, artificial intelligence (AI), and analytical methods. Brain tissue is soaked in a special gel that expands it 16 times, making tiny structures visible under light microscopes. It is the first method after electron microscopy (EM) that can reconstruct all synaptic connections between neurons.
3. What is the primary objective of the MADMAX experiment?
[A] To observe black holes in distant galaxies
[B] To detect dark matter like axions and dark photons
[C] To measure the speed of light in vacuum
[D] None of the Above
Show Answer
Correct Answer: B [To detect dark matter like axions and dark photons]
Notes:
The MADMAX collaboration recently published the first results of its search for dark photons using a prototype detector. MADMAX stands for Magnetised Disk and Mirror Axion Experiment. It is a research project focused on detecting dark matter particles like axions and dark photons. The MADMAX detector uses a system made of sapphire disks and a mirror to form a resonator that enhances detection signals. Dark photons are theoretical particles similar to light particles (photons) but have mass. They are believed to be part of galactic dark matter and can turn into ordinary photons under special conditions.
4. Which country has developed a high-resolution ocean simulation system called LICOMK++ to better study ocean and climate patterns?
[A] Australia
[B] China
[C] Japan
[D] Russia
Show Answer
Correct Answer: B [China]
Notes:
Chinese researchers have recently developed a high-resolution ocean simulation system called LICOMK++ to better study ocean and climate patterns. LICOMK++ stands for Laboratory for Atmospheric and Oceanic Modeling (LASG)/Institute of Atmospheric Physics (IAP) Climate Ocean Model with K++ high-performance computing upgrade. It is described as an ocean “microscope” because of its ultra-high-resolution abilities. This advanced system allows scientists to clearly observe complex ocean processes such as eddies and heat transport. It helps improve the understanding of how oceans influence climate. LICOMK++ can enhance forecasts of extreme weather events like typhoons, marine heatwaves, and floods.
5. Crohn’s disease, that was recently seen in news, is classified as which type of condition?
[A] Autoimmune skin disorder
[B] Chronic inflammatory bowel disease
[C] Lung disease
[D] Cardiovascular disease
Show Answer
Correct Answer: B [Chronic inflammatory bowel disease]
Notes:
A former SpaceX employee has sued the company, claiming he was fired due to Crohn’s disease, a chronic health issue. Crohn’s disease is a type of Inflammatory Bowel Disease (IBD) that causes swelling and irritation in the digestive tract. It often affects the end of the small intestine and the start of the large intestine, but it can impact any part of the tract. The disease causes deep inflammation in the bowel walls, making it painful and hard to manage. Symptoms include diarrhea, stomach cramps, abdominal pain, and weight loss. There is no permanent cure, but treatment can ease symptoms, reduce flare-ups, and help patients live a normal life. This case has drawn attention to workplace rights for people living with chronic medical conditions like Crohn’s disease.
6. The Gravity Recovery and Interior Laboratory (GRAIL) mission was launched by which space agency?
[A] Australian Space Agency
[B] Indian Space Research Organization (ISRO)
[C] European Space Agency (ESA)
[D] National Aeronautics and Space Administration (NASA)
Show Answer
Correct Answer: D [National Aeronautics and Space Administration (NASA) ]
Notes:
NASA’s Gravity Recovery and Interior Laboratory (GRAIL) Mission recently created the most detailed gravity map of the Moon. The Gravity Recovery and Interior Laboratory (GRAIL) mission was launched by NASA. It was part of NASA’s Discovery Program. The new map will help build a precise lunar reference frame and time system, making future Moon missions safer and more accurate. The mission showed that the Moon’s nearside, which faces Earth, is warmer and more geologically active than the farside. Earth’s gravity pulls more on the nearside, causing it to flex more and revealing interior structural differences. The nearside has large flat plains called “mare”, while the farside has rugged terrain.
7. Shingles disease, that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
A recent large-scale study from South Korea, published in the European Heart Journal, found that people vaccinated against shingles have a 23% lower risk of cardiovascular events like heart attacks and strokes. Shingles, or herpes zoster, is caused by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. The virus stays dormant in nerve cells and can reactivate later in life when the immune system weakens. Shingles appears as a painful rash with blisters, usually on one side of the body, and can cause symptoms like burning, headache, and fever. The most common complication is postherpetic neuralgia (PHN), a nerve pain that can last for months. Shingles is not directly contagious but the virus can infect someone who never had chickenpox. It mainly affects people over 50 or those with weak immune systems.
8. Which organization developed the India’s High-Altitude Platform (HAP) prototype, a solar-powered, unmanned aircraft?
[A] National Aerospace Laboratories (NAL)
[B] Bharat Electronics Ltd (BEL)
[C] Indian Space Research Organisation (ISRO)
[D] Defence Research and Development Organisation (DRDO)
Show Answer
Correct Answer: A [National Aerospace Laboratories (NAL)]
Notes:
In a recent development, India’s High-Altitude Platform (HAP) prototype designed by National Aerospace Laboratories (NAL) successfully completed pre-monsoon flight tests with a certified autopilot system. A High-Altitude Platform (HAP) is an unmanned, solar-powered aircraft that flies in the stratosphere at 17 to 22 kilometers altitude. It serves as a middle layer between ground systems and satellites for continuous aerial services. It was developed by NAL, Bengaluru, under the Council of Scientific and Industrial Research (CSIR). The Aeronautical Test Range (ATR) at Chitradurga, Karnataka supported its development. It is designed for border patrolling, surveillance in remote areas, and civil-military use. It can also act as a relay for telecommunications and weather monitoring.
9. Which four countries received WHO’s validation certificates in May 2025 for eliminating industrially produced trans fats?
[A] India, Norway, Oman, Brazil
[B] Norway, Singapore, Oman, Austria
[C] Thailand, South Africa, Oman, Austria
[D] China, Russia, Japan, India
Show Answer
Correct Answer: B [Norway, Singapore, Oman, Austria]
Notes:
On May 19, 2025, the World Health Organization (WHO) honoured Austria, Norway, Oman, and Singapore for eliminating industrially produced trans fats from their national food supply. The announcement was made at the 78th World Health Assembly in Geneva, Switzerland. Trans fats, also called trans-fatty acids (TFA), are harmful unsaturated fats linked to over 278,000 deaths each year. WHO launched the global goal in 2018 to eliminate trans fats by 2025, but progress remains slow. By May 2025, 60 countries had adopted best-practice policies, covering only 46% of the global population. India implemented such a policy in 2022 through the Food Safety and Standards (Prohibition and Restrictions on Sales) Second Amendment Regulations, 2021. India is among the leading Asian countries in enforcing best-practice policies, alongside Thailand.
10. AI Matryoshka is a multi-layered artificial intelligence ecosystem launched by which organization?
[A] Google
[B] Meta
[C] Microsoft
[D] Amazon
Show Answer
Correct Answer: A [Google]
Notes:
At the I/O Developers Conference 2025, Google launched its AI-first restructuring strategy called AI Matryoshka. AI Matryoshka is a multi-layered artificial intelligence ecosystem where Google’s core AI acts like the central brain, similar to a Matryoshka doll. It is built around Gemini 2.5 models and aims to change how users, developers, and enterprises interact with technology. This system powers everything from Application Programming Interfaces (APIs) to user-facing apps. The goal is to deeply embed AI across all Google platforms and create smart, autonomous systems that respond in real time.