1. According to the new study, which medication may be more effective than aspirin for long-term prevention of heart attacks?
[A] Metformin
[B] Clopidogrel
[C] Ibuprofen
[D] Heparin
Show Answer
Correct Answer: B [Clopidogrel]
Notes:
For decades, aspirin was the main drug to prevent heart attacks and strokes. A new study presented at the European Society of Cardiology congress and published in The Lancet shows clopidogrel, a blood-thinning antiplatelet drug, may be more effective. Review of seven clinical trials with 29,000 coronary artery disease patients found clopidogrel 14% more effective than aspirin in lowering major cardiovascular risks. Importantly, there was no higher risk of serious bleeding compared to aspirin. Clopidogrel (a P2Y₁₂ inhibitor) works by blocking platelet receptors to stop dangerous blood clots. It is low-cost, widely available, and safe, making it a strong candidate to replace aspirin in treatment guidelines.
2. Which NASA mission recently spotted two rocky exoplanets orbiting the star TOI-2322?
[A] Transiting Exoplanet Survey Satellite (TESS)
[B] Artemis Program
[C] James Webb Space Telescope
[D] Hubble Space Telescope
Show Answer
Correct Answer: A [Transiting Exoplanet Survey Satellite (TESS)]
Notes:
NASA’s Transiting Exoplanet Survey Satellite (TESS) mission has discovered two rocky exoplanets around star TOI-2322, located 195 light-years away. Scientists detected them by observing small dips in the star’s brightness, indicating planets passing in front. TOI-2322 b is nearly Earth-sized, completes one orbit in 11 days, and has a very hot surface temperature of about 330°C. TOI-2322 c is almost twice Earth’s size, about 18 times heavier, and has a dense structure similar to Earth’s layers. The planets were confirmed using space telescopes and ground tools, showing successful global collaboration in astronomy.
3. Acanthamoeba, recently emerging as a public health concern in Kerala, is what kind of organism?
[A] Free-living amoeba
[B] Bacteria
[C] Virus
[D] Fungus
Show Answer
Correct Answer: A [Free-living amoeba]
Notes:
Acanthamoeba, a free-living amoeba, is now a public health concern in Kerala causing eye (keratitis) and brain infections (amoebic meningoencephalitis). Acanthamoeba is a free-living amoeba found in water, soil, dust, swimming pools, hot tubs, and drinking water systems. It can also exist in humidifiers and heating, ventilation, and air conditioning (HVAC) systems. It causes infections in brain, skin, eyes, and sinuses. It enters through cuts, wounds, inhalation, or contact lens use.
4. Which institute has developed cholesterol-based nanomaterials for quantum technologies and spintronic applications?
[A] Indian Institute of Technology, Delhi
[B] Institute of Nano Science and Technology, Mohali
[C] Indian Institute of Technology, Bombay
[D] Tata Institute of Fundamental Research
Show Answer
Correct Answer: B [Institute of Nano Science and Technology, Mohali]
Notes:
Cholesterol, a fat-like substance, can control the spin of electrons, a quantum property crucial for next-generation spintronic devices. Spintronics uses electron spin to develop energy-efficient electronics and bioelectronic devices. Scientists from the Institute of Nano Science and Technology (INST), Mohali, under the Department of Science and Technology (DST), developed cholesterol-based nanomaterials for spintronic and quantum applications. Cholesterol’s intrinsic handedness (chirality) and flexibility allow precise control over molecular properties. This innovation could enable energy-efficient memory chips and greener quantum technologies.
5. Which organization developed India’s first indigenous multi-stage malaria vaccine (AdFalciVax)?
[A] Indian Council of Medical Research (ICMR)
[B] National Institute of Virology (NIV)
[C] All India Institute of Medical Sciences (AIIMS) New Delhi
[D] Serum Institute of India
Show Answer
Correct Answer: A [Indian Council of Medical Research (ICMR)]
Notes:
India has licensed Indian Immunologicals Limited, Techinvention Lifecare Private Limited, Panacea Biotec Limited, Biological E Limited, and Zydus Lifesciences for manufacturing its first indigenous multi-stage malaria vaccine (AdFalciVax). The vaccine was developed by Indian Council of Medical Research (ICMR) and partners. It targets Plasmodium falciparum before it enters the bloodstream to prevent transmission. The vaccine is affordable, stable, scalable, and effective for over 9 months at room temperature.
6. Which institute has become the first government medical college in India to offer training on the da Vinci Robotic Surgical System?
[A] Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry
[B] Post Graduate Institute of Medical Education & Research, Chandigarh
[C] All India Institute of Medical Sciences, New Delhi (AIIMS New Delhi)
[D] National institute of mental health and Neuro science, Bengaluru
Show Answer
Correct Answer: C [All India Institute of Medical Sciences, New Delhi (AIIMS New Delhi)]
Notes:
AIIMS New Delhi has become the first government medical college in India to offer training on the da Vinci Robotic Surgical System. The advanced system was inaugurated at the Skills, E-Learning and Telemedicine (SET) Facility. AIIMS Delhi now becomes the only institution in India with two robotic systems for training—the da Vinci system and the Hugo robotic trainer by Medtronic. The initiative provides hands-on training for students, residents, nurses, and faculty. Training will cover urology, gynaecology, general surgery, surgical oncology, and head & neck surgery.
7. Scientists at which institute recently discovered how white blood cells adapt their internal skeletons to combat pathogens?
[A] CSIR–Institute of Genomics and Integrative Biology (IGIB)
[B] CSIR–National Chemical Laboratory (NCL)
[C] CSIR–Indian Institute of Chemical Biology (IICB)
[D] CSIR–Centre for Cellular and Molecular Biology (CCMB)
Show Answer
Correct Answer: D [CSIR–Centre for Cellular and Molecular Biology (CCMB)]
Notes:
Scientists at CSIR-Centre for Cellular and Molecular Biology (CCMB) discovered how white blood cells adapt their skeletons to fight pathogens. The study was published in Nature Structural & Molecular Biology. Cell shape depends on a dense, branched actin network near the membrane. Actin molecules push the membrane and create new meshworks for movement. A protein called SPIN90 regulates actin monomers and pairs with the Arp2/3 complex. Together, they grow new actin filaments in two directions about 150° apart. These filaments act as scaffolds to form branched actin mesh, reshaping the cell and aiding motility. This discovery explains rapid immune response and has implications for cancer, immune disorders, and wound healing.
8. Which institute conducted the first successful wheat cultivation experiment in the Thar desert using ‘soilification’ technology?
[A] Banaras Hindu University
[B] Punjab Agricultural University
[C] Central Soil Salinity Research Institute
[D] Central University of Rajasthan
Show Answer
Correct Answer: D [Central University of Rajasthan]
Notes:
Recently, Central University of Rajasthan (CUoR) conducted the first successful wheat cultivation in arid land using desert ‘soilification’ technology. The experiment aims to stop the expansion of western Rajasthan’s Thar desert towards the National Capital Region. Desert sand was converted into soil using polymers and indigenous bioformulation, enhancing water retention and soil structure. The project was supported by Krishi Vigyan Kendra (KVK) and the State Horticulture Department. The experiment proves that even barren desert land can become productive with biotechnology.
9. Which Indian research institute has developed a nanotechnology-based method using the coffee-ring effect to detect toxic molecules like Rhodamine B?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Raman Research Institute (RRI), Bengaluru
[C] National Chemical Laboratory (NCL), Pune
[D] Bhabha Atomic Research Centre (BARC), Mumbai
Show Answer
Correct Answer: B [Raman Research Institute (RRI), Bengaluru]
Notes:
Scientists at the Raman Research Institute (RRI), India developed a sensitive method to detect toxic molecules like Rhodamine B. The method uses the coffee-ring effect combined with nanotechnology for enhanced detection. The coffee-ring effect occurs when a droplet evaporates, and capillary flow moves particles from the center to the edge, forming a ring-shaped deposition pattern. Rhodamine B is a water-soluble synthetic dye with bright pink fluorescence. It is widely used in fluorescence microscopy, flow cytometry, and ELISA biochemical assays. Rhodamine B is toxic and carcinogenic, affecting skin, eyes, and the respiratory system. This method provides a rapid and effective tool for detecting hazardous dyes in research and environmental monitoring.
10. Which space organization launched the PUNCH Space Mission?
[A] Indian Space Research Organisation (ISRO)
[B] National Aeronautics and Space Administration (NASA)
[C] European Space Agency (ESA)
[D] China National Space Administration (CNSA)
Show Answer
Correct Answer: B [National Aeronautics and Space Administration (NASA)]
Notes:
Recently, the PUNCH Space Mission, launched by the National Aeronautics and Space Administration (NASA), observed solar winds. PUNCH stands for Polarimeter to Unify the Corona and Heliosphere. Its aim is to study the Sun’s corona (outer atmosphere) and solar wind as a unified system. The mission has four small satellites in low Earth orbit. They make 3D global observations of the inner heliosphere and map the transition where the corona becomes solar wind.