1. Which country has become the eighth country in the world to introduce the Typhoid Conjugate Vaccine (TCV) into its immunisation programme?
[A] Sri Lanka
[B] Myanmar
[C] Bangladesh
[D] Nepal
Show Answer
Correct Answer: C [Bangladesh]
Notes:
Bangladesh became the 8th country in the world to introduce the Typhoid Conjugate Vaccine (TCV) in its routine immunisation programme. Around 50 million children aged 9 months to 15 years will receive the vaccine under a nationwide campaign. India is the major vaccine supplier for this drive but has not yet included TCV in its Universal Immunisation Programme (UIP). Typhoid fever is caused by the Salmonella typhi bacterium and spreads through contaminated food and water or vectors like flies. The disease can lead to fever lasting several weeks, and complications like intestinal perforation can cause death. The World Health Organization (WHO) estimates 9–12 million global typhoid cases and over 1 lakh deaths annually — with India, Bangladesh, and Pakistan as hotspots
2. Which country has achieved the world’s first conversion of thorium into uranium fuel inside a Thorium Molten Salt Reactor (TMSR)?
[A] Bangladesh
[B] China
[C] Japan
[D] India
Show Answer
Correct Answer: B [China]
Notes:
China has achieved the world’s first conversion of thorium into uranium fuel inside a Thorium Molten Salt Reactor (TMSR). It marks the first-ever experimental data on thorium operation from within a molten salt reactor. The 2 megawatt liquid-fuelled TMSR is currently the only operating reactor successfully using thorium fuel. A Molten Salt Reactor (MSR) is a fourth-generation nuclear reactor using molten salt as both coolant and fuel carrier instead of solid rods.
3. Scrub Typhus, that was recently seen in news, is caused by which microorganism?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: A [Bacteria]
Notes:
A Gulf Keralite’s quick return home for fever treatment proved life-saving after he was diagnosed with scrub typhus. Scrub Typhus is an infectious disease caused by the bacteria Orientia tsutsugamushi. It spreads through bites of infected chiggers (young mites) and not from person to person. Its prevalence depends on factors like climate, vector abundance, farming, domestic animals, and sanitation. The disease is more common during cooler months.
4. The World Health Organisation (WHO) launched its Pandemic Preparedness and Emergency Response site at which Indian institute?
[A] Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh
[B] All India Institute of Medical Sciences (AIIMS), New Delhi
[C] National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru
[D] Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry
Show Answer
Correct Answer: B [All India Institute of Medical Sciences (AIIMS), New Delhi]
Notes:
The World Health Organisation (WHO) launched its Pandemic Preparedness and Emergency Response site at All India Institute of Medical Sciences (AIIMS), New Delhi. This site is part of a global WHO network being set up to conduct rapid investigations and studies during pandemics or epidemics. The goal is to ensure a timely and effective public health response to global health emergencies. The launch was attended by WHO Representative to India, Payden, and AIIMS Director, Dr. M. Srinivas. The site will also operate during non-pandemic periods to maintain continuous readiness and system strength.
5. Which country has discovered a new spider species named Damarchus inazuma?
[A] India
[B] Thailand
[C] China
[D] New Zealand
Show Answer
Correct Answer: B [Thailand]
Notes:
Scientists in Thailand have discovered a new spider species named Damarchus inazuma that is half male and half female. It was found by researchers from Chulalongkorn University in a forest near Nong Rong, Thailand. The spider’s body is perfectly split — left side female with larger fangs and orange colour, and right side male with smaller size and greyish tone. This condition is called gynandromorphism, where an organism has both male and female tissues and traits.
6. ESCAPADE (Escape and Plasma Acceleration and Dynamics Explorers) mission is an initiative of which space agency?
[A] China National Space Administration (CNSA)
[B] European Space Agency (ESA)
[C] Indian Space Research Organisation (ISRO)
[D] National Aeronautics and Space Administration (NASA)
Show Answer
Correct Answer: D [National Aeronautics and Space Administration (NASA)]
Notes:
Blue Origin recently launched NASA’s ESCAPADE mission to Mars. ESCAPADE (Escape and Plasma Acceleration and Dynamics Explorers) is NASA’s first coordinated multi-spacecraft orbital science mission to Mars. It consists of twin orbiters named Blue and Gold that will observe Mars from different locations simultaneously. The mission is part of NASA’s SIMPLEx (Small Innovative Missions for Planetary Exploration) program.
7. Which state has launched KEO, a compact, affordable and AI-ready personal computer, in November 2025?
[A] Karnataka
[B] Kerala
[C] Maharashtra
[D] Gujarat
Show Answer
Correct Answer: A [Karnataka]
Notes:
On November 17, 2025, Karnataka’s Department of Electronics, IT & BT, with KEONICS, launched KEO, a compact, affordable and AI-ready personal computer designed entirely in Karnataka. KEO stands for Knowledge-driven, Economical, Open-source, built on an open-source RISC-V processor with a Linux-based OS. It features an on-device AI core that works without internet and includes BUDDH, an AI agent trained on the Karnataka DSERT syllabus to help students in low-connectivity areas. KEO will be deployed across schools, universities, businesses, homes and government offices, supporting locally adaptable, home-grown computing.
8. What is the name of India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease?
[A] SCD-CURE
[B] GEN-EDIT 1
[C] BIRSA 101
[D] HematoGene
Show Answer
Correct Answer: C [BIRSA 101]
Notes:
India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.
9. GLP-1 Drug, that was recently seen in news, is used for the treatment of which disease?
[A] Foot and Mouth disease
[B] Typhoid
[C] Tuberculosis
[D] Obesity
Show Answer
Correct Answer: D [Obesity]
Notes:
The World Health Organization has issued the first global guidelines on Glucagon-Like Peptide-1 (GLP-1) drugs for weight loss. GLP-1 receptor agonists are synthetic medicines used to treat adult obesity and type-2 diabetes. These drugs are mainly injectable, while oral versions are under development. Leading examples are Semaglutide and Tirzepatide, now available in India. They increase insulin, reduce glucagon, slow stomach emptying, and suppress appetite, helping control blood sugar and body weight.
10. Which telescope was used to discover the spiral galaxy “Alaknanda” ?
[A] Hubble Space Telescope
[B] Spitzer Space Telescope
[C] Chandra X-ray Observatory
[D] James Webb Space Telescope
Show Answer
Correct Answer: D [James Webb Space Telescope]
Notes:
Researchers at National Centre for Radio Astrophysics – Tata Institute of Fundamental Research (NCRA–TIFR), Pune, discovered a new spiral galaxy named Alaknanda. It lies 12 billion light years away and shows a perfect spiral structure. The name comes from the Alaknanda River and the Hindi word for the Milky Way. The galaxy spans 30,000 light years, with two clear spiral arms around a bright central bulge. It forms stars rapidly, producing 60 solar masses per year. It resembles a young Milky Way, formed when our galaxy was only 10% of its current age. The discovery was made using National Aeronautics and Space Administration (NASA)’s James Webb Space Telescope (JWST).