Science & Technology Current Affairs MCQs

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A recent study in the New England Journal of Medicine found that a weekly dose of semaglutide shows strong results in treating Metabolic Dysfunction-Associated Steatohepatitis (MASH). Semaglutide is a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, first developed to treat Type 2 diabetes. It is the main ingredient in medicines like Ozempic, used for diabetes, and Wegovy, used for weight loss. MASH is a severe type of fatty liver disease caused by metabolic problems and not by alcohol. It involves fat buildup, inflammation, and liver scarring, and is linked to obesity, diabetes, and overnutrition. If not treated, MASH can lead to cirrhosis or liver failure.

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Indian and US researchers have recently discovered a new subtype of Maturity-Onset Diabetes of the Young (MODY), a rare, inherited form of diabetes. MODY is caused by genetic mutations that lead to impaired insulin production or function. It is typically diagnosed in adolescents or young adults under 35 years of age, without significant obesity. The discovery was made by researchers from the Madras Diabetes Research Foundation (MDRF) in Chennai and Washington University School of Medicine in St. Louis. This breakthrough could change the way certain forms of MODY are diagnosed and treated, offering better solutions for patients. MODY is divided into 14 subtypes, each linked to different gene mutations.

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Kerala recently reported a new case of Nipah virus infection, highlighting the state’s renewed struggle with this rare and deadly zoonotic virus. The Nipah virus, according to the World Health Organization (WHO), is a newly emerging zoonosis, meaning it is transmitted from animals to humans. The virus primarily spreads through fruit bats and contaminated food, making it a significant public health threat. Nipah virus infection progresses rapidly, and there is no specific treatment available for it. The virus is known for its high fatality rate and the potential for human-to-human transmission.

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Scientists recently developed a new technique called Light-microscopy-based Connectomics (LICONN) to map brain cell connections using light microscopes. LICONN was developed at the Institute of Science and Technology Austria (ISTA). It allows mapping of brain’s complex neural networks at the nanoscale and also identifies specific molecules in those connections. LICONN combines light microscopy with hydrogel expansion, fluorescent stains, artificial intelligence (AI), and analytical methods. Brain tissue is soaked in a special gel that expands it 16 times, making tiny structures visible under light microscopes. It is the first method after electron microscopy (EM) that can reconstruct all synaptic connections between neurons.

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Researchers have recently found that magnetar flares can create heavy elements like gold using a process called rapid neutron-capture or r-process nucleosynthesis. Magnetars are a special type of neutron star with extremely powerful magnetic fields—about a thousand times stronger than normal neutron stars. These stars sometimes release huge flares of energy, and one such giant flare in 2004 helped scientists make this discovery. The flare was observed by NASA’s Compton Gamma Ray Observatory, which recorded strange gamma-ray signals nearly a day later. These delayed signals did not match typical afterglows but showed signs of radioactive decay from neutron-rich elements. This proves that r-process nucleosynthesis, earlier linked mainly to neutron star mergers, can also happen in magnetar flares. This recent evidence changes our understanding of where rare elements like gold in the universe might come from.

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The MADMAX collaboration recently published the first results of its search for dark photons using a prototype detector. MADMAX stands for Magnetised Disk and Mirror Axion Experiment. It is a research project focused on detecting dark matter particles like axions and dark photons. The MADMAX detector uses a system made of sapphire disks and a mirror to form a resonator that enhances detection signals. Dark photons are theoretical particles similar to light particles (photons) but have mass. They are believed to be part of galactic dark matter and can turn into ordinary photons under special conditions.

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Chinese researchers have recently developed a high-resolution ocean simulation system called LICOMK++ to better study ocean and climate patterns. LICOMK++ stands for Laboratory for Atmospheric and Oceanic Modeling (LASG)/Institute of Atmospheric Physics (IAP) Climate Ocean Model with K++ high-performance computing upgrade. It is described as an ocean “microscope” because of its ultra-high-resolution abilities. This advanced system allows scientists to clearly observe complex ocean processes such as eddies and heat transport. It helps improve the understanding of how oceans influence climate. LICOMK++ can enhance forecasts of extreme weather events like typhoons, marine heatwaves, and floods.

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India has launched its first 3-nanometre (3nm) chip design centres in Noida and Bengaluru, marking a major step in advanced semiconductor development. These centres have been set up by Renesas Electronics India Private Limited, placing India among a few nations working on next-generation chip design. The initiative is part of a broader government plan to build a complete semiconductor ecosystem including design, fabrication, ATMP (Assembly, Testing, Marking, and Packaging), and supply chain support.

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Astronomers from the Russian Academy of Sciences recently detected 11 new Active Galactic Nuclei (AGNs) using the Spektr-RG (SRG) space observatory. AGNs are regions at the centers of galaxies emitting extremely high levels of electromagnetic radiation, often outshining the galaxy itself. This emission comes from matter being consumed by a supermassive black hole or intense star formation activity. AGNs are essential for understanding galaxy formation and evolution due to their immense energy output.

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The Union Cabinet recently approved a new semiconductor manufacturing unit in Uttar Pradesh, marking a significant step in India’s semiconductor ambitions. This facility is the sixth under the India Semiconductor Mission, a push for self-reliance in semiconductor technology. The unit is a joint venture between HCL and Foxconn and will be located near Jewar Airport in the Yamuna Expressway Industrial Development Authority (YEIDA) region. It will manufacture display driver chips for devices like mobile phones, laptops, automobiles, and more. The plant will have a production capacity of 20,000 wafers per month, with a target output of 36 million chips monthly.