41. Which cities have been selected for the development of the four Hydrogen Valley Innovation Clusters (HVICs) in India?
[A] Pune, Jodhpur, Bhubaneswar, Kerala
[B] Mumbai, Jaipur, Hyderabad, Tamil Nadu
[C] Bengaluru, Lucknow, Indore, Kerala
[D] Bhopal, Jaipur, Varanasi, Karnataka
Show Answer
Correct Answer: A [Pune, Jodhpur, Bhubaneswar, Kerala]
Notes:
The Union Minister of State (Independent Charge) for Science and Technology announced the development of four Hydrogen Valley Innovation Clusters (HVICs) across India. Hydrogen Valley Innovation Clusters (HVICs) aim to demonstrate the full green hydrogen value chain, from production, storage, transport to utilization. The project has a total investment of ₹485 crore. HVICs aim to build a local hydrogen ecosystem, connecting supply and demand across transport, industry, and energy, while fostering research, innovation, and skills. The four clusters are being developed in Pune, Jodhpur, Bhubaneswar, and Kerala.
42. What are “Foraminifera” that were recently seen in news?
[A] Single-celled marine organisms
[B] Flowering plant species
[C] Coral species
[D] Invasive weed
Show Answer
Correct Answer: A [Single-celled marine organisms]
Notes:
A global review has identified 57 new living species of foraminifera. Foraminifera, or forams, are single-celled marine organisms found in oceans, coasts, and estuaries. Most have shells and are either planktonic (float in water) or benthic (live on sea floor). They are generally under 500 microns in size, though some tropical species reach 20 cm. Their name comes from foramen (Latin for window), with holes in shells for pseudopodia to gather food. They eat detritus, diatoms, bacteria, algae, and tiny animals like copepods. Shells are made of calcium carbonate (calcareous) or sand grains (agglutinate) with one or multiple coiled chambers.
43. What is the name of India’s first indigenous CRISPR-based gene therapy for Sickle Cell Disease?
[A] SCD-CURE
[B] GEN-EDIT 1
[C] BIRSA 101
[D] HematoGene
Show Answer
Correct Answer: C [BIRSA 101]
Notes:
India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.
44. Which organizations have indigenously built the India’s first private PSLV rocket?
[A] Hindustan Aeronautics Limited and L&T – Larsen & Toubro
[B] Defence Research and Development Organisation and Tata Group
[C] Indian Space Research Organisation and BHEL – Bharat Heavy Electricals Limited
[D] Bharat Electronics Limited and Defence Research and Development Organisation
Show Answer
Correct Answer: A [Hindustan Aeronautics Limited and L&T – Larsen & Toubro]
Notes:
The Hindustan Aeronautics Limited (HAL)–Larsen & Toubro (L&T) consortium has indigenously built India’s first private Polar Satellite Launch Vehicle (PSLV). The PSLV is scheduled to launch the Oceansat satellite early next year. India’s Indian Space Research Organisation (ISRO) signed a 2022 contract with the HAL–L&T consortium for end-to-end production of five PSLV-XL rockets. This move shifts PSLV manufacturing from ISRO to industry partners while ISRO focuses on new missions and research. The consortium has faced production challenges, resolved with ISRO’s support. HAL also received technology for the Small Satellite Launch Vehicle (SSLV) to fully own and operate its production.
45. Which country has declared an outbreak of leptospirosis after the destruction caused by Hurricane Melissa in November 2025?
[A] Cuba
[B] Trinidad and Tobago
[C] Jamaica
[D] Barbados
Show Answer
Correct Answer: C [Jamaica]
Notes:
Recently, Jamaica declared an outbreak of leptospirosis after the destruction caused by Hurricane Melissa. Leptospirosis is a fatal bacterial disease. It is caused by the bacterium Leptospira interrogans, also called Leptospira. The bacteria enter the human body through tiny cracks or wounds in the skin, especially on the feet. It is more common in warm and humid regions across both urban and rural areas. The disease is contagious in animals and occasionally infects humans under suitable environmental conditions.
46. The Entrepreneur-in-Residence (EIR) Programme is implemented by which government department?
[A] Department for Promotion of Industry and Internal Trade
[B] Department of Biotechnology
[C] Department of Commerce
[D] Department of Science and Technology
Show Answer
Correct Answer: D [Department of Science and Technology ]
Notes:
The Entrepreneur-in-Residence Programme is becoming popular among young startups and innovators. It works under the National Initiative for Developing and Harnessing Innovations which is NIDHI. It encourages graduate students to choose entrepreneurship as a career. It provides financial and non-financial support in the form of a fellowship. It offers startup infrastructure, mentoring, technical guidance, and industry support. It is implemented by the Department of Science and Technology with NCL Venture Centre.
47. Where is the headquarters of International Astronomical Union (IAU) located?
[A] Paris
[B] Geneva
[C] Rome
[D] Beijing
Show Answer
Correct Answer: A [Paris]
Notes:
A 3.5-billion-year-old crater on Mars is named after Indian geologist M. S. Krishnan. The naming was approved by the International Astronomical Union. The International Astronomical Union was founded in 1919. It promotes astronomy research, education, and global cooperation. It standardizes astronomical constants and naming of celestial bodies. It alone has the authority to name planets, craters, and space features. It holds a General Assembly every three years. Its headquarters is in Paris.
48. Where was India’s first single-use bioprocess design and scale-up facility inaugurated in November 2025?
[A] Bengaluru
[B] Kolkata
[C] Hyderabad
[D] Chennai
Show Answer
Correct Answer: C [Hyderabad]
Notes:
Telangana’s 1 Bio, India’s first single-use bioprocess design and scale-up facility, was inaugurated at Genome Valley, Hyderabad. It was created to solve the lack of affordable bioprocess scale-up infrastructure despite Telangana’s strong biotech talent. The facility supports start-ups and big companies with end-to-end process development and pilot validation. It was developed by the Government of Telangana, Telangana Lifesciences, Department of Biotechnology (DBT), Government of India, and Telangana Industrial Infrastructure Corporation (TGIIC). It has 500-litre bioreactors, advanced processing systems, and analytical labs.
49. What is the name of India’s first manned deep-sea submersible mission?
[A] Gaganyaan
[B] Samudrayaan
[C] Sagaryaan
[D] Chandrayaan
Show Answer
Correct Answer: B [Samudrayaan]
Notes:
Samudrayaan is India’s first manned deep-ocean submersible mission to reach 6,000 metres depth. Testing is delayed due to late supply of syntactic foam from France, now expected by year-end after testing in Norway. The project is led by National Institute of Ocean Technology under the Ministry of Earth Sciences. A steel model has been tested up to 100 metres; a 500-metre trial is planned by April next year. The final titanium hull, built by Indian Space Research Organisation, will be tested in Russia. The mission will carry three crew members to collect seabed soil and rocks for future deep-sea mining.
50. GLP-1 Drug, that was recently seen in news, is used for the treatment of which disease?
[A] Foot and Mouth disease
[B] Typhoid
[C] Tuberculosis
[D] Obesity
Show Answer
Correct Answer: D [Obesity]
Notes:
The World Health Organization has issued the first global guidelines on Glucagon-Like Peptide-1 (GLP-1) drugs for weight loss. GLP-1 receptor agonists are synthetic medicines used to treat adult obesity and type-2 diabetes. These drugs are mainly injectable, while oral versions are under development. Leading examples are Semaglutide and Tirzepatide, now available in India. They increase insulin, reduce glucagon, slow stomach emptying, and suppress appetite, helping control blood sugar and body weight.