Science & Technology Current Affairs MCQs

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Indian space-tech startup Dhruva Space is set to launch its first commercial satellite mission named LEAP-1. LEAP-1 will carry payloads for Artificial Intelligence (AI) and Earth observation. It uses the indigenously developed P-30 satellite platform, which was space-qualified on ISRO’s PSLV-C58 in January 2024 during the LEAP-TD mission. The mission is jointly developed by Dhruva Space, Akula Tech (Australia), and Esper Satellites (Australia).

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The World Health Organization (WHO) and International Agency for Research on Cancer (IARC) have classified Hepatitis D virus (HDV) as carcinogenic to humans, alongside Hepatitis B (HBV) and Hepatitis C (HCV). HBV, HCV, and HDV infect over 300 million people globally, causing 1.3 million deaths annually from liver cirrhosis and cancer. HDV affects about 5% of chronic HBV patients, mainly in Asia, Africa, Amazon Basin, and high-risk groups like drug users and haemodialysis patients. Co-infection with HBV raises liver cancer risk 2–6 times; 75% may develop cirrhosis within 15 years. No separate HDV vaccine exists; prevention relies on universal HBV vaccination and testing.

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National Aeronautics and Space Administration (NASA) has unveiled the second Crew Health and Performance Exploration Analog (CHAPEA) habitat. It is designed for analogue missions simulating year-long stays on Mars. The second mission will begin in late 2025 with four crew members. The 1,700 square foot, 3D-printed habitat will be used to test living in isolation. CHAPEA (Crew Health and Performance Exploration Analog) is a program of analog missions that simulate year-long stays on the Martian surface. The inaugural CHAPEA mission began in June 2023 and concluded in July 2024, providing valuable insights into the challenges of living and working on Mars.

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The Department of Animal Husbandry & Dairying (DAHD) under the Ministry of Fisheries, Animal Husbandry & Dairying has recently issued the Revised National Action Plan on Glanders. Glanders is caused by the bacterium Burkholderia mallei and mainly affects equines like horses, mules, and donkeys, with risks to other animals and humans. It causes nodules and ulcerations in the respiratory tract and lungs, with a skin form known as farcy. Transmission occurs through contaminated food or water, infected harness equipment, or horse meat. It is a World Organisation for Animal Health (WOAH)-listed disease and must be notified under the WOAH Terrestrial Animal Health Code.

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Prime Minister of India welcomed the agreement between Indian Space Research Organisation (ISRO) and Japan Aerospace Exploration Agency (JAXA) for the Chandrayaan-5 mission under the Lunar Polar Exploration (LUPEX) programme. LUPEX is jointly developed by ISRO and JAXA to explore the Moon’s southern polar region. The mission aims to investigate the presence of water and other elements, potentially as surface ice, and demonstrate innovative surface exploration technologies. It features a lander developed by ISRO and a rover developed by JAXA. The rover will autonomously search for water-rich areas, drill, sample soil, and analyze it with onboard instruments.

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Acanthamoeba, a free-living amoeba, is now a public health concern in Kerala causing eye (keratitis) and brain infections (amoebic meningoencephalitis). Acanthamoeba is a free-living amoeba found in water, soil, dust, swimming pools, hot tubs, and drinking water systems. It can also exist in humidifiers and heating, ventilation, and air conditioning (HVAC) systems. It causes infections in brain, skin, eyes, and sinuses. It enters through cuts, wounds, inhalation, or contact lens use.

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India has licensed Indian Immunologicals Limited, Techinvention Lifecare Private Limited, Panacea Biotec Limited, Biological E Limited, and Zydus Lifesciences for manufacturing its first indigenous multi-stage malaria vaccine (AdFalciVax). The vaccine was developed by Indian Council of Medical Research (ICMR) and partners. It targets Plasmodium falciparum before it enters the bloodstream to prevent transmission. The vaccine is affordable, stable, scalable, and effective for over 9 months at room temperature.

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Recently, a study in Nature Reviews Disease Primers gave an in-depth analysis of sarcoidosis. Sarcoidosis is an inflammatory disease where immune cells form granulomas in organs, mainly lungs. Granulomas are most common in lungs and lymph nodes but can also affect eyes, skin, heart, and other organs. Exact cause is unknown but linked to genetic changes and triggers like bacteria, viruses, dust, or chemicals. Symptoms range from mild to severe, including cough, breathlessness, shin sores, eye pain, and redness. Some cases resolve on their own, while others become chronic and may lead to fibrosis with lung scarring. There is no cure, but treatment with medicines reduces immune overreaction and prevents organ damage.

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A viral infection called Hand, Foot, and Mouth Disease (HFMD) is spreading rapidly among children in Delhi and Haryana, prompting advisories. It is a highly contagious illness caused by a virus. It causes blister-like rashes on hands and feet, painful mouth sores, and sometimes rashes on chest, back, arms, legs, genitals, and buttocks. It mostly affects infants and children under 5 years, spreading quickly in schools and daycare. It is different from foot-and-mouth disease in animals, caused by a different virus. Transmission happens through unwashed hands, saliva, mucus, feces, or blister fluid. No cure or vaccine exists; recovery usually takes 7–10 days with basic care. Complications are rare, but children under 2 may take longer to recover.

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Researchers at Stanford University and the Arc Institute created the world’s first entirely AI-generated genome. The AI-designed virus can infect and kill bacteria, acting as a bacteriophage. Artificial Intelligence (AI) model named Evo was used, employing genome “language models” to design complete viral genomes. Evo was trained on about 2 million viral genomes to learn DNA patterns, gene order, and composition. Scientists guided Evo to mimic phiX174, a small bacteriophage with 11 genes and approximately 5,000 DNA letters. This achievement marks a significant advancement beyond AI-designed proteins or small multi-gene systems. It demonstrates AI’s potential to innovate in synthetic biology and genome engineering.