41. Lunar Polar Exploration (LUPEX) programme is jointly developed by which two space agencies?
[A] National Aeronautics and Space Administration (NASA) and European Space Agency (ESA)
[B] China National Space Administration (CNSA) and European Space Agency (ESA)
[C] Indian Space Research Organisation (ISRO) and European Space Agency (ESA)
[D] Japan Aerospace Exploration Agency (JAXA) and Indian Space Research Organisation (ISRO)
Show Answer
Correct Answer: D [Japan Aerospace Exploration Agency (JAXA) and Indian Space Research Organisation (ISRO)]
Notes:
Prime Minister of India welcomed the agreement between Indian Space Research Organisation (ISRO) and Japan Aerospace Exploration Agency (JAXA) for the Chandrayaan-5 mission under the Lunar Polar Exploration (LUPEX) programme. LUPEX is jointly developed by ISRO and JAXA to explore the Moon’s southern polar region. The mission aims to investigate the presence of water and other elements, potentially as surface ice, and demonstrate innovative surface exploration technologies. It features a lander developed by ISRO and a rover developed by JAXA. The rover will autonomously search for water-rich areas, drill, sample soil, and analyze it with onboard instruments.
42. By using which method did scientists study fossil leaves from Nagaland to understand the evolution of Indian monsoons?
[A] Radiocarbon Dating
[B] Ice Core Analysis
[C] Dendrochronology
[D] CLAMP (Climate Leaf Analysis Multivariate Program)
Show Answer
Correct Answer: D [CLAMP (Climate Leaf Analysis Multivariate Program)]
Notes:
A study of fossil leaves from Nagaland revealed how Antarctica influenced the Indian Monsoons. Fossil leaves from the Laisong Formation in Nagaland revealed that the region once had a warm and wet climate with very high rainfall and temperatures. The fossils matched the period when massive ice sheets began forming in Antarctica, showing a global connection. Growth of Antarctic ice reshaped global wind and rainfall patterns by shifting the Intertropical Convergence Zone (ITCZ) toward the tropics. This shift brought intense monsoonal rains to Northeast India and led to the evolution of the monsoon system. The research used CLAMP (Climate Leaf Analysis Multivariate Program) method to analyze fossil leaves. CLAMP treats fossil leaves as “climate fingerprints” to reconstruct past climates.
43. What kind of disease is “Sarcoidosis” that was recently seen in news?
[A] Autoimmune inflammatory disease
[B] Nutritional deficiency disorder
[C] Neurological disorder
[D] None of the Above
Show Answer
Correct Answer: A [Autoimmune inflammatory disease]
Notes:
Recently, a study in Nature Reviews Disease Primers gave an in-depth analysis of sarcoidosis. Sarcoidosis is an inflammatory disease where immune cells form granulomas in organs, mainly lungs. Granulomas are most common in lungs and lymph nodes but can also affect eyes, skin, heart, and other organs. Exact cause is unknown but linked to genetic changes and triggers like bacteria, viruses, dust, or chemicals. Symptoms range from mild to severe, including cough, breathlessness, shin sores, eye pain, and redness. Some cases resolve on their own, while others become chronic and may lead to fibrosis with lung scarring. There is no cure, but treatment with medicines reduces immune overreaction and prevents organ damage.
44. Hand, Foot, and Mouth Disease (HFMD), that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
A viral infection called Hand, Foot, and Mouth Disease (HFMD) is spreading rapidly among children in Delhi and Haryana, prompting advisories. It is a highly contagious illness caused by a virus. It causes blister-like rashes on hands and feet, painful mouth sores, and sometimes rashes on chest, back, arms, legs, genitals, and buttocks. It mostly affects infants and children under 5 years, spreading quickly in schools and daycare. It is different from foot-and-mouth disease in animals, caused by a different virus. Transmission happens through unwashed hands, saliva, mucus, feces, or blister fluid. No cure or vaccine exists; recovery usually takes 7–10 days with basic care. Complications are rare, but children under 2 may take longer to recover.
45. Japanese Encephalitis (JE), that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: B [Virus]
Notes:
Mosquito-borne diseases like dengue fever are rising due to rapid urbanisation, climate change, and global travel. A new study published on 3 September in Science Translational Medicine shows waning immunity against Japanese Encephalitis Virus (JEV) can worsen dengue outcomes. Japanese Encephalitis (JE) is a viral zoonotic disease caused by the Japanese Encephalitis (B) virus. Transmission occurs through infected Culex mosquitoes of the Vishnui group, not from human to human. It is most common in rural Asia, especially during monsoon seasons. Both viruses belong to the genus Orthoflavivirus and show cross-immune interactions.
46. Lecanemab drug, that was recently seen in news, is used to treat which disease?
[A] Multiple Sclerosis
[B] Tuberculosis
[C] Alzheimer’s Disease
[D] Huntington’s Disease
Show Answer
Correct Answer: C [Alzheimer’s Disease]
Notes:
Australia recently approved Lecanemab for early-stage Alzheimer’s disease. Dementia causes progressive memory and thinking problems and is now Australia’s leading cause of death. Alzheimer’s disease accounts for 60-80% of dementia cases. Lecanemab is a monoclonal antibody drug that targets amyloid proteins in the brain. It aims to slow disease progression by tackling the cause of Alzheimer’s, not just symptoms. The drug works by using antibodies to mark amyloid for removal by brain immune cells, preventing toxicity to brain cells.
47. What is “WISPIT 2b” that was recently seen in news?
[A] A gas giant planet forming inside a protoplanetary disk
[B] A newly discovered asteroid in the Solar System
[C] A comet orbiting a distant star
[D] None of the Above
Show Answer
Correct Answer: A [A gas giant planet forming inside a protoplanetary disk]
Notes:
Astronomers have directly imaged a young planet, WISPIT 2b, forming inside a gap in a protoplanetary disk around a distant star. The discovery confirms that disk gaps are indeed caused by growing planets. WISPIT 2b is a gas giant, about five times the mass of Jupiter, and only five million years old. It orbits WISPIT 2, a young star 437 light-years from Earth. Protoplanetary disks are rings of gas and dust around young stars, providing planet-forming material. The planet was imaged using Very Large Telescope (VLT), MagAO-X on Magellan Clay Telescope, and Large Binocular Telescope.
48. The new crop varieties ‘Pant Urd-13, Pant Urd-14, Pant Matar 554, and Pant Jau 1106’ were launched in which state?
[A] Gujarat
[B] Uttarakhand
[C] Maharashtra
[D] Uttar Pradesh
Show Answer
Correct Answer: B [Uttarakhand]
Notes:
On October 12, 2025, Uttarakhand Chief Minister Pushkar Singh Dhami inaugurated newly developed pulse and barley varieties at the 118th All India Farmers Fair and Agricultural Industry Exhibition held at GB Pant University of Agriculture and Technology (GBPUAT) in Uttarakhand. The varieties were developed by GBPUAT students to improve crop productivity and farmer income. Pant Urd-13 and Pant Urd-14 are improved urdbean (black gram) varieties with higher yield and better disease resistance. Pant Matar 554 is a high-yielding pea variety designed to enhance farmers’ earnings. Pant Jau 1106 is a new barley variety introduced to diversify crop options for farmers in the region.
49. Which Indian lunar mission made the first-ever observation of the effect of the Sun’s coronal mass ejection (CME) on the Moon?
[A] Chandrayaan-1
[B] Chandrayaan-2
[C] Chandrayaan-3
[D] Aditya-L1
Show Answer
Correct Answer: B [Chandrayaan-2]
Notes:
Chandrayaan-2, India’s second lunar mission, made the first direct observation of the Sun’s Coronal Mass Ejection (CME) effects on the Moon. The observation was made by CHACE-2 (Chandra’s Atmospheric Composition Explorer-2), a payload onboard the orbiter. Indian Space Research Organisation (ISRO) reported that the dayside lunar exosphere pressure increased when the CME impacted the Moon. The total number density of neutral atoms or molecules increased more than tenfold, confirming theoretical predictions for the first time. Chandrayaan-2, launched on 22 July 2019 via GSLV Mk-III M1, carried eight experiment payloads; however, the Vikram lander lost communication during its soft-landing attempt.
50. Which institute has discovered that Sinapic acid can accelerate wound healing in diabetic conditions?
[A] Jawaharlal Nehru University
[B] Nagaland University
[C] Banaras Hindu University
[D] University of Delhi
Show Answer
Correct Answer: B [Nagaland University]
Notes:
Researchers at Nagaland University discovered that Sinapic acid significantly accelerates wound healing in diabetic conditions. Sinapic acid is a natural phenolic acid derived from cinnamic acid. It has antioxidant, antitumor, anti-inflammatory, antibacterial, and neuroprotective properties. It is found in spices, citrus and berry fruits, vegetables, cereals, and oilseed crops. The compound activates the SIRT1 (Sirtuin 1) pathway, aiding tissue repair, angiogenesis, and inflammation control. This discovery could lead to safe, natural, and effective diabetic wound treatments. Diabetic wounds are slow-healing sores, mostly on the foot, increasing risk of neuropathy, poor circulation, infections, and amputation. Diabetes mellitus is a metabolic disease causing high blood glucose levels and affects hundreds of millions globally.