Science & Technology Current Affairs MCQs

Notes:
Scientists at the Bose Institute, Kolkata have developed GlowCas9, a CRISPR protein that glows during gene editing. It is a bioluminescent Cas9, created by fusing Cas9 with a split nano-luciferase enzyme from deep-sea shrimp proteins. GlowCas9 is highly stable, retaining structure and activity even at higher temperatures. When Cas9 folds correctly, the luciferase pieces reconnect and produce light, enabling real-time, non-harmful tracking of gene editing in cells, tissues, and plant leaves. It improves the precision of Homology-Directed Repair (HDR), a key DNA repair process for genetic diseases like sickle cell anaemia and muscular dystrophy. GlowCas9 advances theratracking, the visual monitoring of molecular gene therapy in action.

Notes:
India launched DHRUV64, the country’s first 1.0 GHz, 64-bit dual-core microprocessor, fully developed by the Centre for Development of Advanced Computing (C-DAC) under the Microprocessor Development Programme. DHRUV64 aims to reduce India’s dependence on imported processors and supports both strategic and commercial applications. The processor features modern architectural enhancements for improved efficiency, multitasking, and reliability, and integrates seamlessly with hardware for applications like 5G, automotive systems, consumer electronics, industrial automation, and the Internet of Things. India contributes nearly 20% to global microprocessor production, highlighting the importance of indigenous chip development.

Notes:
Kavach is an indigenously developed Automatic Train Protection (ATP) system designed to improve railway operational safety across the Indian Railways network. It was developed by the Research Design and Standards Organisation (RDSO) of Indian Railways. As of December 2025, the system has been commissioned on over 2,000 km of railway routes, with 7,129 km of Optical Fibre Cable (OFC) laid, 860 telecom towers installed, 767 stations connected, 3,413 km of trackside equipment deployed, and 4,154 locomotives fitted with Kavach. About 40,000 technicians and operators have been trained, reflecting the scale of operational readiness.

Notes:
The Indian Space Research Organisation (ISRO) recently launched RESPOND Basket 2025. The programme invites research proposals from premier universities and recognised academic and R&D institutions. It focuses on areas relevant to ISRO’s upcoming missions and national priorities. RESPOND Basket 2025 supports projects including the Bharatiya Antariksh Station, Chandrayaan-4, Gaganyaan missions, Venus orbiter, and a human Moon landing. The initiative aims to strengthen collaboration between ISRO and academic institutions and foster research aligned with India’s space ambitions.

Notes:
Astronomers discovered a strange exoplanet named PSR J2322-2650b using the James Webb Space Telescope. The planet is nearly as massive as Jupiter and orbits a pulsar, a dead star emitting strong energy beams. This system is a “black widow pulsar” system, where the pulsar slowly damages the planet with radiation. PSR J2322-2650b has a lemon or football-like shape, stretched by the pulsar’s strong gravity, unlike normal round planets. Its atmosphere is mostly helium and carbon, with clouds of carbon soot that may form diamond rain. The planet orbits extremely close to the pulsar—about 1 million miles away, completing a full orbit in 8 hours.

Notes:
A new monoclonal antibody treatment shows promise for primary sclerosing cholangitis (PSC), a rare liver disease. Primary Sclerosing Cholangitis (PSC) is a long-term condition causing inflammation, scarring, and narrowing of bile ducts, leading to liver damage. Bile ducts carry bile from the liver to the gallbladder and small intestine for digestion. Primary Sclerosing Cholangitis (PSC) can cause liver failure and increase risk of cancers of the bile ducts, gallbladder, and colon.

Notes:
Russia plans to build a nuclear power plant on the Moon by 2036 to support its lunar space programme and the joint Russian-Chinese International Lunar Research Station. The project is aimed at powering rovers, observatories, and infrastructure for a permanently functioning scientific lunar station, moving from one-time missions to long-term lunar exploration. The Moon, 384,400 km from Earth, stabilizes Earth’s axis and creates ocean tides, making it strategically important for scientific and exploration purposes.

Notes:
The Institute of Kidney Diseases and Research Centre (IKDRC-ITS) at Ahmedabad Civil Medical College completed 500 kidney transplants in 2025, setting a national record for a public hospital. Institute of Kidney Diseases and Research Centre (IKDRC-ITS) is the only government-run hospital in India to perform 500 kidney transplants in a single year, reinforcing its leadership in kidney transplantation. The institute operates under Gujarat government’s Health Department and provides advanced medical care to economically weaker patients.

Notes:
Recently, an observational study on cellulitis was published in the International Journal of Lower Extremity Wounds. Cellulitis is a common skin infection caused mainly by Streptococcus and Staphylococcus bacteria. It usually affects the legs, feet, and toes but can also involve face, arms, hands, and fingers. The infection affects tissues beneath the skin. Risk factors include skin wounds or a weakened immune system, which allow bacteria to enter easily. Cellulitis is generally not contagious, except rarely through open-wound contact with an infected person.

Notes:
Recently, the Defence Research and Development Organisation (DRDO) developed a portable desalination device named Sea Water Desalination System (SWaDeS). It is designed to meet drinking water needs of soldiers in remote and field conditions. The system can be manually operated or engine-driven and was developed by Defence Laboratory, Jodhpur for Tri-command services. The manual version can be carried by one person and supports 10–12 personnel during emergencies. It is suitable for naval operations, coastal areas, and inland saline regions like Pangong Tso in Ladakh.