Science & Technology Current Affairs MCQs

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Scientists at the Bose Institute, Kolkata have developed GlowCas9, a CRISPR protein that glows during gene editing. It is a bioluminescent Cas9, created by fusing Cas9 with a split nano-luciferase enzyme from deep-sea shrimp proteins. GlowCas9 is highly stable, retaining structure and activity even at higher temperatures. When Cas9 folds correctly, the luciferase pieces reconnect and produce light, enabling real-time, non-harmful tracking of gene editing in cells, tissues, and plant leaves. It improves the precision of Homology-Directed Repair (HDR), a key DNA repair process for genetic diseases like sickle cell anaemia and muscular dystrophy. GlowCas9 advances theratracking, the visual monitoring of molecular gene therapy in action.

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Indian Institute of Technology Bombay (IIT Bombay) has hosted ATMAN 3.0, an eight-week Health Technology (HealthTech) accelerator programme. The programme is conducted by the Technology Innovation Hub (TIH) at IIT Bombay. ATMAN 3.0 is supported by the National Mission on Interdisciplinary Cyber-Physical Systems (NM-ICPS) and the Department of Science and Technology (DST). It aims to transform early-stage HealthTech startups into investment-ready ventures. Thirteen startups were selected from 173 applicants after a competitive pitching process. Each selected startup can receive seed funding support of one crore rupees or more. The programme will conclude with a Demo Day on 9 January 2026 at Novotel, Mumbai International Airport.

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A new study warns that heavy use of artemisinin and favourable conditions can create new hotspots of drug resistance, with resistance markers slowly rising in parts of Africa. Artemisinin is an antimalarial drug obtained from the sweet wormwood plant called Artemisia annua. It was discovered in the 1970s and became a major breakthrough when malaria parasites developed resistance to older drugs like chloroquine. It is effective against all malaria-causing parasites of the Plasmodium genus, mainly during the blood stage. Artemisinin quickly reduces parasites but stays in the body for a short time, so it is combined with other drugs. The World Health Organization recommends artemisinin-based combination therapies as the standard treatment for Plasmodium falciparum malaria.

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India launched DHRUV64, the country’s first 1.0 GHz, 64-bit dual-core microprocessor, fully developed by the Centre for Development of Advanced Computing (C-DAC) under the Microprocessor Development Programme. DHRUV64 aims to reduce India’s dependence on imported processors and supports both strategic and commercial applications. The processor features modern architectural enhancements for improved efficiency, multitasking, and reliability, and integrates seamlessly with hardware for applications like 5G, automotive systems, consumer electronics, industrial automation, and the Internet of Things. India contributes nearly 20% to global microprocessor production, highlighting the importance of indigenous chip development.

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Researchers from Bose Institute, Kolkata, in collaboration with L V Prasad Eye Institute, Hyderabad, have developed a peptide therapy for fungal keratitis, a severe infection of the cornea. They designed a 15-residue peptide, SA-XV, derived from the host-defense peptide S100A12, previously known to inhibit fungal growth. SA-XV acts by interacting with fungal cell walls and membranes, translocating into the cytoplasm, binding nuclear DNA to halt the cell cycle, and targeting mitochondria to induce apoptosis.

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The Indian Computer Emergency Response Team (CERT-In) warned about a new cyber threat targeting WhatsApp users called GhostPairing. GhostPairing is a hacking technique where attackers secretly link their device to a victim’s WhatsApp account. It allows near-complete access without passwords, SIM swap, or user awareness. Hackers gain control by tricking users into entering WhatsApp pairing codes. The attack starts with a message from a trusted contact saying, “Hi, check this photo.” The message contains a link with a Facebook-style preview. The link opens a fake Facebook viewer asking users to verify to see the content. Victims are prompted to enter their phone number and code. This process unknowingly gives attackers full control of the WhatsApp account.

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A new monoclonal antibody treatment shows promise for primary sclerosing cholangitis (PSC), a rare liver disease. Primary Sclerosing Cholangitis (PSC) is a long-term condition causing inflammation, scarring, and narrowing of bile ducts, leading to liver damage. Bile ducts carry bile from the liver to the gallbladder and small intestine for digestion. Primary Sclerosing Cholangitis (PSC) can cause liver failure and increase risk of cancers of the bile ducts, gallbladder, and colon.

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A Legionnaires’ disease outbreak triggered a health alert in Sydney’s central business district, urging people to watch for symptoms. Legionnaires’ disease is a severe lung infection (pneumonia) caused by the bacterium Legionella. The disease was named after a 1976 outbreak at an American Legion convention in the United States. Legionella occurs naturally in freshwater sources like lakes, rivers and soil. Infection mainly happens by inhaling contaminated water droplets or soil particles. It does not spread from person to person and is not contagious. Older adults, smokers and immunocompromised people are at higher risk

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Candida auris is a multidrug-resistant fungal pathogen spreading globally and becoming more deadly. Indian researchers from Vallabhbhai Patel Chest Institute, University of Delhi, in collaboration with the US National Institutes of Health, led the study. The fungus can grow and persist on human skin, inside the body (e.g., gut), or in the environment. Invasive infections caused by C. auris affect about 6.5 million people annually. It can cause serious infections including bloodstream infections, meningitis, bone infections, burn/wound infections, and urinary tract infections. The pathogen is gaining virulence and poses a significant global health threat.

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The Union Minister Shri Rajiv Ranjan Singh inaugurated India’s first commercial-scale tropical Recirculating Aquaculture System (RAS)–based Rainbow Trout Aquaculture Farm & Research Institute on 5th January 2026 in Hyderabad, Telangana. The facility, established by Smart Green Aquaculture Limited at Kandukur Mandal, Ranga Reddy District, demonstrates year-round farming of high-value cold-water species like Rainbow Trout in tropical climates using precision engineering and advanced water recirculation technologies. The project serves as a live training and demonstration platform, providing youth hands-on experience in advanced aquaculture systems, automation, and biosecurity, strengthening human capital in the fisheries sector.