41. Which institute developed a gold nanocluster-based biosensor for early detection of Parkinson’s Disease?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Institute of Nano Science and Technology (INST), Mohali
[C] All India Institute of Medical Sciences (AIIMS), Delhi
[D] Indian Council of Medical Research (ICMR)
Show Answer
Correct Answer: B [Institute of Nano Science and Technology (INST), Mohali]
Notes:
Researchers at the Institute of Nano Science and Technology (INST), Mohali, are developing a nanotechnology-based tool for early detection of Parkinson’s Disease (PD). Parkinson’s Disease (PD) is a rapidly growing neurological disorder in India, often diagnosed after significant neurodegeneration. The team focused on α-synuclein, a protein that changes from harmless to toxic forms, damaging brain cells. They created gold nanoclusters (AuNCs), ultrasmall particles coated with amino acids to selectively bind normal or toxic protein forms. The tool enables early-stage detection, improving treatment, quality of life, and reducing healthcare costs.
42. Which city has reported a surge in Guillain-Barré Syndrome (GBS) in August 2025?
[A] Jerusalem
[B] Gaza
[C] Tehran
[D] Damascus
Show Answer
Correct Answer: B [Gaza]
Notes:
Gaza has recently reported a surge in Guillain-Barré Syndrome (GBS), raising health concerns. Guillain-Barré Syndrome (GBS) is a rare autoimmune condition where the immune system attacks the peripheral nervous system. The peripheral nervous system controls muscle movement, pain, temperature, and touch sensations. It is also called Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP). It commonly affects people between 30 and 50 years of age. It usually follows viral or bacterial infections, vaccination, or surgery.
43. Which country has launched its advanced JUPITER space camera aboard the National Advanced Optical System (NAOS) satellite?
[A] Australia
[B] Israel
[C] Iran
[D] Japan
Show Answer
Correct Answer: B [Israel]
Notes:
Israeli defense technology firm Elbit Systems recently launched its advanced JUPITER space camera aboard the National Advanced Optical System (NAOS) satellite. The satellite was launched from Vandenberg Space Force Base, California, on a SpaceX Falcon 9 rocket. JUPITER supports military operations, environmental monitoring, scientific research, and wide-span observation missions. It features a large aperture, lightweight design, high-resolution panchromatic channel for black-and-white imaging, and a Near Infrared (NIR) channel for vegetation, water, and material analysis. The camera can capture continuous long image strips covering large areas efficiently.
44. Which district in Gujarat has been identified as a Mars-analogue site due to the presence of jarosite deposits?
[A] Banaskantha
[B] Junagadh
[C] Kutch
[D] Bhavnagar
Show Answer
Correct Answer: C [Kutch]
Notes:
Matanomadh, a remote village in Kutch district, Gujarat, may serve as a test bed for ISRO’s Mangalyaan-2 mission to Mars. Researchers from Space Applications Centre (SAC) Ahmedabad, Savitribai Phule Pune University (SPPU), and Birbal Sahni Institute of Palaeosciences, Lucknow dated jarosite mineral in Matanomadh to 55 million years (Paleocene period). Jarosite is a yellow, iron-rich sulphate mineral, similar to those found on Mars, indicating past water activity. The site allows field-analogue studies for Mars, including rover testing, drilling, geochemistry, and astrobiology research. The discovery can help decode Martian geology, past chemical interactions, and organic molecule trapping, aiding future Mars missions.
45. Lunar Polar Exploration (LUPEX) programme is jointly developed by which two space agencies?
[A] National Aeronautics and Space Administration (NASA) and European Space Agency (ESA)
[B] China National Space Administration (CNSA) and European Space Agency (ESA)
[C] Indian Space Research Organisation (ISRO) and European Space Agency (ESA)
[D] Japan Aerospace Exploration Agency (JAXA) and Indian Space Research Organisation (ISRO)
Show Answer
Correct Answer: D [Japan Aerospace Exploration Agency (JAXA) and Indian Space Research Organisation (ISRO)]
Notes:
Prime Minister of India welcomed the agreement between Indian Space Research Organisation (ISRO) and Japan Aerospace Exploration Agency (JAXA) for the Chandrayaan-5 mission under the Lunar Polar Exploration (LUPEX) programme. LUPEX is jointly developed by ISRO and JAXA to explore the Moon’s southern polar region. The mission aims to investigate the presence of water and other elements, potentially as surface ice, and demonstrate innovative surface exploration technologies. It features a lander developed by ISRO and a rover developed by JAXA. The rover will autonomously search for water-rich areas, drill, sample soil, and analyze it with onboard instruments.
46. Which institute has proposed a mission called PRATUSH to study the Cosmic Dawn?
[A] Raman Research Institute (RRI), Bengaluru
[B] Physical Research Laboratory (PRL), Ahmedabad
[C] Indian Institute of Astrophysics (IIA), Bengaluru
[D] None of the Above
Show Answer
Correct Answer: A [Raman Research Institute (RRI), Bengaluru]
Notes:
Scientists at Raman Research Institute (RRI) proposed a mission called PRATUSH to study the Cosmic Dawn. PRATUSH stands for Probing ReionizATion of the Universe using Signal from Hydrogen. It is a radio telescope to be placed on the far side of the Moon. It is built by Raman Research Institute (RRI) Bengaluru with collaboration from Indian Space Research Organisation (ISRO). It will use a wideband antenna (30–250 MHz), a self-calibratable analog receiver, and a digital correlator with 100 kHz spectral resolution. It will observe large sky regions continuously and record spectra of radio emission. Its nominal lifetime is two years to collect high-quality data.
47. Which NASA mission recently spotted two rocky exoplanets orbiting the star TOI-2322?
[A] Transiting Exoplanet Survey Satellite (TESS)
[B] Artemis Program
[C] James Webb Space Telescope
[D] Hubble Space Telescope
Show Answer
Correct Answer: A [Transiting Exoplanet Survey Satellite (TESS)]
Notes:
NASA’s Transiting Exoplanet Survey Satellite (TESS) mission has discovered two rocky exoplanets around star TOI-2322, located 195 light-years away. Scientists detected them by observing small dips in the star’s brightness, indicating planets passing in front. TOI-2322 b is nearly Earth-sized, completes one orbit in 11 days, and has a very hot surface temperature of about 330°C. TOI-2322 c is almost twice Earth’s size, about 18 times heavier, and has a dense structure similar to Earth’s layers. The planets were confirmed using space telescopes and ground tools, showing successful global collaboration in astronomy.
48. Which institute has developed cholesterol-based nanomaterials for quantum technologies and spintronic applications?
[A] Indian Institute of Technology, Delhi
[B] Institute of Nano Science and Technology, Mohali
[C] Indian Institute of Technology, Bombay
[D] Tata Institute of Fundamental Research
Show Answer
Correct Answer: B [Institute of Nano Science and Technology, Mohali]
Notes:
Cholesterol, a fat-like substance, can control the spin of electrons, a quantum property crucial for next-generation spintronic devices. Spintronics uses electron spin to develop energy-efficient electronics and bioelectronic devices. Scientists from the Institute of Nano Science and Technology (INST), Mohali, under the Department of Science and Technology (DST), developed cholesterol-based nanomaterials for spintronic and quantum applications. Cholesterol’s intrinsic handedness (chirality) and flexibility allow precise control over molecular properties. This innovation could enable energy-efficient memory chips and greener quantum technologies.
49. What kind of disease is “Sarcoidosis” that was recently seen in news?
[A] Autoimmune inflammatory disease
[B] Nutritional deficiency disorder
[C] Neurological disorder
[D] None of the Above
Show Answer
Correct Answer: A [Autoimmune inflammatory disease]
Notes:
Recently, a study in Nature Reviews Disease Primers gave an in-depth analysis of sarcoidosis. Sarcoidosis is an inflammatory disease where immune cells form granulomas in organs, mainly lungs. Granulomas are most common in lungs and lymph nodes but can also affect eyes, skin, heart, and other organs. Exact cause is unknown but linked to genetic changes and triggers like bacteria, viruses, dust, or chemicals. Symptoms range from mild to severe, including cough, breathlessness, shin sores, eye pain, and redness. Some cases resolve on their own, while others become chronic and may lead to fibrosis with lung scarring. There is no cure, but treatment with medicines reduces immune overreaction and prevents organ damage.
50. Scientists at which institute recently discovered how white blood cells adapt their internal skeletons to combat pathogens?
[A] CSIR–Institute of Genomics and Integrative Biology (IGIB)
[B] CSIR–National Chemical Laboratory (NCL)
[C] CSIR–Indian Institute of Chemical Biology (IICB)
[D] CSIR–Centre for Cellular and Molecular Biology (CCMB)
Show Answer
Correct Answer: D [CSIR–Centre for Cellular and Molecular Biology (CCMB)]
Notes:
Scientists at CSIR-Centre for Cellular and Molecular Biology (CCMB) discovered how white blood cells adapt their skeletons to fight pathogens. The study was published in Nature Structural & Molecular Biology. Cell shape depends on a dense, branched actin network near the membrane. Actin molecules push the membrane and create new meshworks for movement. A protein called SPIN90 regulates actin monomers and pairs with the Arp2/3 complex. Together, they grow new actin filaments in two directions about 150° apart. These filaments act as scaffolds to form branched actin mesh, reshaping the cell and aiding motility. This discovery explains rapid immune response and has implications for cancer, immune disorders, and wound healing.