41. Glanders disease, that was recently seen in news, is caused by which agent?
[A] Bacteria
[B] Virus
[C] Fungus
[D] Protozoa
Show Answer
Correct Answer: A [Bacteria]
Notes:
The Department of Animal Husbandry & Dairying (DAHD) under the Ministry of Fisheries, Animal Husbandry & Dairying has recently issued the Revised National Action Plan on Glanders. Glanders is caused by the bacterium Burkholderia mallei and mainly affects equines like horses, mules, and donkeys, with risks to other animals and humans. It causes nodules and ulcerations in the respiratory tract and lungs, with a skin form known as farcy. Transmission occurs through contaminated food or water, infected harness equipment, or horse meat. It is a World Organisation for Animal Health (WOAH)-listed disease and must be notified under the WOAH Terrestrial Animal Health Code.
42. What is “Climaconeis heteropolaris” that was recently mentioned in news?
[A] A new species of fish
[B] A new species of diatom
[C] A new type of bacteria
[D] A new variety of seaweed
Show Answer
Correct Answer: B [A new species of diatom]
Notes:
A team of Indian and international researchers has discovered a new diatom species named Climaconeis heteropolaris in Udupi estuarine waters. It was found where the Sita and Swarna rivers meet before entering the Arabian Sea, Karnataka. Diatoms are photosynthetic, single-celled microscopic algae forming a key part of phytoplankton. They are found in lakes, ponds, rivers, streams, and oceans worldwide. Some float freely in water, while others attach to plants, rocks, or sediments as benthic diatoms. Diatoms produce oxygen, support aquatic life, and generate up to 50% of global atmospheric oxygen annually. They are vital in nutrient cycling of both marine and freshwater ecosystems.
43. Researchers have found evidence that interstellar dust grains align with magnetic fields in the Milky Way. Interstellar dust grains are composed of which materials?
[A] Iron and nickel
[B] Silicates and carbonaceous material
[C] Hydrogen and helium
[D] Oxygen and nitrogen
Show Answer
Correct Answer: B [Silicates and carbonaceous material]
Notes:
Scientists have found that tiny interstellar dust grains act as storytellers of the universe. A team led by the Indian Institute of Astrophysics (IIA), Bengaluru, provided the strongest observational evidence of how these dust grains align with magnetic fields in the Milky Way. Dust grains are a few micrometers in size, made of silicates and carbonaceous material, and exist throughout the interstellar medium. They play a key role in star and planet formation and cause starlight polarization detected since 1949.
44. Acanthamoeba, recently emerging as a public health concern in Kerala, is what kind of organism?
[A] Free-living amoeba
[B] Bacteria
[C] Virus
[D] Fungus
Show Answer
Correct Answer: A [Free-living amoeba]
Notes:
Acanthamoeba, a free-living amoeba, is now a public health concern in Kerala causing eye (keratitis) and brain infections (amoebic meningoencephalitis). Acanthamoeba is a free-living amoeba found in water, soil, dust, swimming pools, hot tubs, and drinking water systems. It can also exist in humidifiers and heating, ventilation, and air conditioning (HVAC) systems. It causes infections in brain, skin, eyes, and sinuses. It enters through cuts, wounds, inhalation, or contact lens use.
45. Where was India’s largest lithium-ion battery manufacturing plant launched?
[A] Gujarat
[B] Rajasthan
[C] Madhya Pradesh
[D] Haryana
Show Answer
Correct Answer: D [Haryana]
Notes:
India’s largest Lithium-ion (Li-ion) battery manufacturing plant was inaugurated in Haryana on 5 September 2025. When fully operational, it will produce 20 crore battery packs annually, meeting nearly 40% of India’s 50 crore pack requirement. The plant was set up under the Centre’s Electronics Manufacturing Cluster (EMC) scheme. Li-ion batteries are rechargeable, with lithium ions moving between graphite (negative electrode) and lithium metal oxides (positive electrode) through a non-aqueous electrolyte. They offer high energy density (75-200 Wh/kg), are lightweight, use fewer toxic metals, and provide good cycle stability and efficiency. They have low self-discharge and no memory effect, ensuring reliable performance.
46. Which institute discovered that protein p47 acts as a “mechanical chaperone”, enhancing protein stability under mechanical stress?
[A] Indian Institute of Science (IISc), Bengaluru
[B] S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata
[C] National Chemical Laboratory (NCL), Pune
[D] Centre for Cellular and Molecular Biology (CCMB), Hyderabad
Show Answer
Correct Answer: B [S. N. Bose National Centre for Basic Sciences (SNBNCBS), Kolkata]
Notes:
Researchers at S. N. Bose National Centre for Basic Sciences (SNBNCBS) discovered protein p47’s new role as a “mechanical chaperone.” P47 is a cofactor protein known for assisting p97 in protein trafficking, degradation, and membrane fusion. Study revealed p47 boosts mechanical efficiency of protein extraction from endoplasmic reticulum (ER) to cytoplasm. It stabilizes polypeptides under stress, guides them through pores, prevents misfolding, and improves translocation. This is the first single-molecule evidence of autonomous, force-dependent chaperone-like activity by p47. Discovery opens new therapeutic possibilities for diseases linked to protein instability.
47. Which country has launched EnteroMix, a new mRNA-based cancer vaccine?
[A] Russia
[B] China
[C] India
[D] Australia
Show Answer
Correct Answer: A [Russia]
Notes:
Russia has launched EnteroMix, a new mRNA-based cancer vaccine, reported to show 100 percent efficacy in early trials. It was developed by the National Medical Research Radiology Centre (NMRRC) and Engelhardt Institute of Molecular Biology under the Russian Academy of Sciences. The launch took place at the St Petersburg International Economic Forum (SPIEF 2025) and shared globally via Sputnik news service. The vaccine targets colorectal cancer first, with versions in development for glioblastoma and melanoma. EnteroMix uses four harmless viruses to attack cancer cells and boost immune defence. Russian Federal Medical and Biological Agency (FMBA) confirmed its safety for repeated use and personalised RNA-based tailoring.
48. By using which method did scientists study fossil leaves from Nagaland to understand the evolution of Indian monsoons?
[A] Radiocarbon Dating
[B] Ice Core Analysis
[C] Dendrochronology
[D] CLAMP (Climate Leaf Analysis Multivariate Program)
Show Answer
Correct Answer: D [CLAMP (Climate Leaf Analysis Multivariate Program)]
Notes:
A study of fossil leaves from Nagaland revealed how Antarctica influenced the Indian Monsoons. Fossil leaves from the Laisong Formation in Nagaland revealed that the region once had a warm and wet climate with very high rainfall and temperatures. The fossils matched the period when massive ice sheets began forming in Antarctica, showing a global connection. Growth of Antarctic ice reshaped global wind and rainfall patterns by shifting the Intertropical Convergence Zone (ITCZ) toward the tropics. This shift brought intense monsoonal rains to Northeast India and led to the evolution of the monsoon system. The research used CLAMP (Climate Leaf Analysis Multivariate Program) method to analyze fossil leaves. CLAMP treats fossil leaves as “climate fingerprints” to reconstruct past climates.
49. What is the name of the half-humanoid robot that ISRO will send in December 2025 as part of the first uncrewed Gaganyaan mission?
[A] Aditya
[B] Vyommitra
[C] Kaveri
[D] Talwar
Show Answer
Correct Answer: B [Vyommitra]
Notes:
ISRO Chief V. Narayanan announced that a half-humanoid robot Vyommitra will be sent in December 2025 as part of the first uncrewed Gaganyaan mission. Two more uncrewed missions are planned in 2026 before sending India’s first astronaut, Gaganyatri, to space in early 2027. ISRO successfully conducted the first Integrated Air Drop Test (IADT-01) for the parachute-based deceleration system with support from the Indian Air Force, DRDO, Navy, and Coast Guard. Human Rated Launch Vehicle (HLVM3), Crew Escape System, and propulsion systems have been tested.
50. The SODAR (Sound Detection and Ranging) system facility was designed and developed by which institute?
[A] CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal
[B] CSIR-Central Building Research Institute (CBRI), Roorkee
[C] CSIR-Central Electronics Engineering Research Institute (CEERI), Pilani
[D] CSIR-Central Scientific Instruments Organisation (CSIO), Chandigarh
Show Answer
Correct Answer: A [CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal]
Notes:
On Council of Scientific & Industrial Research (CSIR’s) Foundation Day, 26th September 2025, the SODAR (Sound Detection and Ranging) system facility was inaugurated at the India Meteorological Department (IMD), Delhi. The facility was designed and developed by CSIR–Advanced Materials and Processes Research Institute (AMPRI), Bhopal. The SODAR system will provide additional atmospheric data for improved weather forecasting and research.