Science & Technology Current Affairs MCQs

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Mosquito-borne diseases like dengue fever are rising due to rapid urbanisation, climate change, and global travel. A new study published on 3 September in Science Translational Medicine shows waning immunity against Japanese Encephalitis Virus (JEV) can worsen dengue outcomes. Japanese Encephalitis (JE) is a viral zoonotic disease caused by the Japanese Encephalitis (B) virus. Transmission occurs through infected Culex mosquitoes of the Vishnui group, not from human to human. It is most common in rural Asia, especially during monsoon seasons. Both viruses belong to the genus Orthoflavivirus and show cross-immune interactions.

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Australia recently approved Lecanemab for early-stage Alzheimer’s disease. Dementia causes progressive memory and thinking problems and is now Australia’s leading cause of death. Alzheimer’s disease accounts for 60-80% of dementia cases. Lecanemab is a monoclonal antibody drug that targets amyloid proteins in the brain. It aims to slow disease progression by tackling the cause of Alzheimer’s, not just symptoms. The drug works by using antibodies to mark amyloid for removal by brain immune cells, preventing toxicity to brain cells.

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Recent research shows that eating diets high in Ultra Processed Foods (UPFs) can worsen gut inflammation and increase Crohn’s disease flare-ups. Crohn’s Disease is a chronic Inflammatory Bowel Disease (IBD) that causes swelling and irritation in the digestive tract. It usually affects the small intestine and the beginning of the large intestine. Inflammation can spread deep into the bowel layers, causing pain and serious complications. Common symptoms include diarrhea, abdominal cramps, and weight loss. It mostly develops between ages 20 and 29. The exact cause is unknown but may involve genes, immune reactions, and the microbiome. There is no cure, but treatment helps control symptoms and maintain remission.

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In October 2025, scientists discovered a new exoplanet named GJ 251c, located less than 20 light-years from Earth. The discovery was made by an international team, including researchers from Penn State University (PSU), USA. The finding was published in The Astronomical Journal. GJ 251c is a super-Earth, about four times the mass of Earth and likely rocky in composition. It was detected using the radial-velocity method, with data from the Habitable Zone Planet Finder (HPF) at PSU’s Hobby-Eberly Telescope (HET). The discovery provides key insights into planetary formation and the search for potentially habitable exoplanets.

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Russia has successfully tested its new atomic-powered and nuclear-capable underwater drone named Poseidon. President Vladimir Putin announced the test, calling it a major success and saying it cannot be intercepted. The test took place just days after Russia also tested the Burevestnik nuclear-powered cruise missile. Both tests are seen as signals to the United States amid the ongoing Ukraine conflict. The Poseidon drone was tested using nuclear power for the first time. It reportedly surpasses all current systems in speed and depth. Its nuclear reactor is 100 times smaller than those on submarines. The drone’s nuclear warhead is said to be more powerful than the Sarmat Intercontinental Ballistic Missile (ICBM).

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Bangladesh became the 8th country in the world to introduce the Typhoid Conjugate Vaccine (TCV) in its routine immunisation programme. Around 50 million children aged 9 months to 15 years will receive the vaccine under a nationwide campaign. India is the major vaccine supplier for this drive but has not yet included TCV in its Universal Immunisation Programme (UIP). Typhoid fever is caused by the Salmonella typhi bacterium and spreads through contaminated food and water or vectors like flies. The disease can lead to fever lasting several weeks, and complications like intestinal perforation can cause death. The World Health Organization (WHO) estimates 9–12 million global typhoid cases and over 1 lakh deaths annually — with India, Bangladesh, and Pakistan as hotspots

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In November 2025, the European Space Agency (ESA) and Arianespace launched the Copernicus Sentinel-1D Earth Observation Satellite (EOS) to Low Earth Orbit (LEO) aboard the Ariane 6 rocket from the Guiana Space Centre, French Guiana. The mission, designated VA265, marked a key step in strengthening Europe’s autonomous access to space and Earth observation capability. It is the fourth and final satellite of the first-generation Copernicus Sentinel-1 constellation, completing Europe’s radar imaging network.

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In November 2025, the World Health Organization (WHO) confirmed an outbreak of Rift Valley Fever (RVF) in Mauritania and Senegal, Western Africa. Rift Valley Fever is caused by a Phlebovirus from the Phenuiviridae family. It mainly affects animals such as sheep, goats, cattle, and camels. Humans get infected through contact with infected animals or mosquito bites. It does not spread from person to person. The disease was first identified in Kenya’s Rift Valley in the 1930s. It later spread across sub-Saharan Africa, Egypt, Saudi Arabia, and Yemen.

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Recently, IIT Bombay developed India’s first Quantum Diamond Microscope under the National Quantum Mission. The microscope uses Nitrogen-Vacancy (NV) centres in diamond to image magnetic fields at nanoscale resolution at room temperature. It enables advanced research in neuroscience, materials science, and non-destructive semiconductor testing. This innovation marks India’s first patent in quantum sensing technology. The development strengthens India’s national capability in frontier quantum instrumentation and promotes technological self-reliance in advanced scientific research.

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India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.