Science & Technology Current Affairs MCQs

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India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.

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Recently, Jamaica declared an outbreak of leptospirosis after the destruction caused by Hurricane Melissa. Leptospirosis is a fatal bacterial disease. It is caused by the bacterium Leptospira interrogans, also called Leptospira. The bacteria enter the human body through tiny cracks or wounds in the skin, especially on the feet. It is more common in warm and humid regions across both urban and rural areas. The disease is contagious in animals and occasionally infects humans under suitable environmental conditions.

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Researchers at Indian Institute of Technology Madras developed India’s first Indigenous Vessel Traffic Management System (VTMS) for ports. The system was built by the National Technology Centre for Ports, Waterways and Coasts (NTCPWC) as per guidelines of the Ministry of Ports, Shipping and Waterways (MoSPW), Government of India. It gives India full control over source code, data, and vessel movement information, ensuring high maritime security. The VTMS is cost-effective, secure, scalable, and easy to maintain.

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Indian scientists developed a new Artificial Intelligence (AI) tool to improve cancer diagnosis and treatment at the molecular level. The tool, called OncoMark, was created by S. N. Bose National Centre for Basic Sciences and Ashoka University under the Department of Science and Technology (DST). It studies cancer through biological “hallmarks” like metastasis, immune evasion, and genomic instability. It goes beyond Tumor–Node–Metastasis (TNM) staging, which often misses hidden tumor behavior. The model was trained on 3.1 million single cells from 14 cancer types. It achieved over 99% accuracy in internal testing and 96% accuracy on patient data.

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ISRO Chairman V Narayanan inaugurated Ananth Technologies’ Ananth Centre of Excellence for Navigation (ACEN) in Thiruvananthapuram. ACEN is India’s first private-sector navigation innovation hub. Ananth Technologies, founded in 1992, contributes to ISRO and Defence Research and Development Organisation (DRDO) missions with expertise in precision sensors, airworthiness, and system integration. Navigation is crucial for missiles, aircraft, ships, and satellites; reliance on foreign GPS revealed strategic vulnerabilities. ACEN will handle Maintenance, Repair, and Overhaul (MRO) of navigation systems domestically.

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The Ebola outbreak in the Democratic Republic of Congo (DRC) is declared over after 42 days without new cases, confirmed by Democratic Republic of Congo (DRC) health officials and the World Health Organization (WHO). Ebola, caused by orthoebolaviruses, first discovered in 1976 in DRC near the Ebola River, leads to severe hemorrhagic fever with internal bleeding. It spreads from wild animals like fruit bats and non-human primates, and among humans through direct contact with infected body fluids, not through air.

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India launched its first hydrogen-powered water taxi service in Varanasi on December 10, 2025. The service was inaugurated by Union Minister of Ports, Shipping & Waterways Sarbananda Sonowal, marking a major advancement in India’s clean transport initiatives. The water taxi has been built by Cochin Shipyard, integrating modern engineering with sustainability. It operates on a hybrid electric–hydrogen propulsion system, ensuring zero emissions, low noise levels and high environmental safety. The vessel is equipped with five hydrogen cylinders and 3 kW solar panels, which help meet auxiliary power needs.

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A new study warns that heavy use of artemisinin and favourable conditions can create new hotspots of drug resistance, with resistance markers slowly rising in parts of Africa. Artemisinin is an antimalarial drug obtained from the sweet wormwood plant called Artemisia annua. It was discovered in the 1970s and became a major breakthrough when malaria parasites developed resistance to older drugs like chloroquine. It is effective against all malaria-causing parasites of the Plasmodium genus, mainly during the blood stage. Artemisinin quickly reduces parasites but stays in the body for a short time, so it is combined with other drugs. The World Health Organization recommends artemisinin-based combination therapies as the standard treatment for Plasmodium falciparum malaria.

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BharatNet is an ambitious Government of India project approved in 2011 to provide broadband connectivity to all Gram Panchayats (GPs) in the country. It aims to offer open and unrestricted broadband access to telecom operators, Internet Service Providers (ISPs), Cable TV operators, and content providers to enable services such as e-health, e-education, and e-governance in rural areas. Phase I is complete and Phase II is ongoing and aims to connect 1.5 lakh additional Gram Panchayats. Phase III is ongoing and focuses on future-proofing the network by integrating 5G technology.

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The Indian Space Research Organisation (ISRO) recently launched RESPOND Basket 2025. The programme invites research proposals from premier universities and recognised academic and R&D institutions. It focuses on areas relevant to ISRO’s upcoming missions and national priorities. RESPOND Basket 2025 supports projects including the Bharatiya Antariksh Station, Chandrayaan-4, Gaganyaan missions, Venus orbiter, and a human Moon landing. The initiative aims to strengthen collaboration between ISRO and academic institutions and foster research aligned with India’s space ambitions.