Science & Technology Current Affairs MCQs
61. Which institute has discovered a host protein that uses tiny tweezer-like machines to kill germs before they harm the body?
[A] IIT Bombay
[B] IIT Kanpur
[C] IIT Delhi
[D] IIT Ahmedabad
[B] IIT Kanpur
[C] IIT Delhi
[D] IIT Ahmedabad
Correct Answer: A [IIT Bombay]
Notes:
Researchers at the Indian Institute of Technology (IIT) Bombay discovered a host protein that uses tiny tweezer-like machines to kill germs before they harm the body. The study, led by Professor Anirban Banerjee, found that this protein works like a special operation unit to detect and neutralize threats. When bacteria attack, human cells tag them as a “Red Flag” using a protein called “Ubiquitin.” Cells then target the flagged bacteria, tearing apart their surface proteins, similar to piranhas attacking prey. This discovery could help fight antibiotic-resistant bacteria, offering hope for more effective treatments against infections.
Researchers at the Indian Institute of Technology (IIT) Bombay discovered a host protein that uses tiny tweezer-like machines to kill germs before they harm the body. The study, led by Professor Anirban Banerjee, found that this protein works like a special operation unit to detect and neutralize threats. When bacteria attack, human cells tag them as a “Red Flag” using a protein called “Ubiquitin.” Cells then target the flagged bacteria, tearing apart their surface proteins, similar to piranhas attacking prey. This discovery could help fight antibiotic-resistant bacteria, offering hope for more effective treatments against infections.
62. Which coal PSU has become the first in India to adopt Paste Fill Technology in underground mining?
[A] Eastern Coalfields Limited (ECL)
[B] Central Coalfields Limited (CCL)
[C] Mahanadi Coalfields Limited (MCL)
[D] South Eastern Coalfields Limited (SECL)
[B] Central Coalfields Limited (CCL)
[C] Mahanadi Coalfields Limited (MCL)
[D] South Eastern Coalfields Limited (SECL)
Correct Answer: D [South Eastern Coalfields Limited (SECL)]
Notes:
South Eastern Coalfields Limited (SECL) has become the first coal Public Sector Undertaking (PSU) in India to adopt Paste Fill Technology in underground mining. Paste Fill Technology is a modern method used in underground mining to fill the empty spaces left after coal extraction. The paste used is made by mixing crushed overburden from opencast mines, fly ash, cement, water, and binding chemicals. This technique eliminates the need for acquiring additional surface land. It also helps prevent land subsidence, making mining operations more environmentally friendly and safe.
South Eastern Coalfields Limited (SECL) has become the first coal Public Sector Undertaking (PSU) in India to adopt Paste Fill Technology in underground mining. Paste Fill Technology is a modern method used in underground mining to fill the empty spaces left after coal extraction. The paste used is made by mixing crushed overburden from opencast mines, fly ash, cement, water, and binding chemicals. This technique eliminates the need for acquiring additional surface land. It also helps prevent land subsidence, making mining operations more environmentally friendly and safe.
63. The Phenome India project was launched by which institution?
[A] Indian Institute of Science (IISc) Bengaluru
[B] Bhabha Atomic Research Centre (BARC)
[C] Council of Scientific and Industrial Research (CSIR)
[D] Indian Institute of Technology Delhi
[B] Bhabha Atomic Research Centre (BARC)
[C] Council of Scientific and Industrial Research (CSIR)
[D] Indian Institute of Technology Delhi
Correct Answer: C [Council of Scientific and Industrial Research (CSIR)]
Notes:
Recently, concerns were raised when the Department of Biotechnology (DBT) called for proposals using GenomeIndia data without sharing important phenotype data details. Phenome India-CSIR Health Cohort Knowledgebase (PI-CheCK) was launched by the Council of Scientific and Industrial Research (CSIR) on December 7, 2023. The project aims to build India-specific risk prediction models for cardio-metabolic diseases like diabetes, liver, and heart diseases. It is India’s first pan-India longitudinal health study focused on cardio-metabolic health.
Recently, concerns were raised when the Department of Biotechnology (DBT) called for proposals using GenomeIndia data without sharing important phenotype data details. Phenome India-CSIR Health Cohort Knowledgebase (PI-CheCK) was launched by the Council of Scientific and Industrial Research (CSIR) on December 7, 2023. The project aims to build India-specific risk prediction models for cardio-metabolic diseases like diabetes, liver, and heart diseases. It is India’s first pan-India longitudinal health study focused on cardio-metabolic health.
64. Global Antibiotic Research and Development Partnership (GARDP) was created by which organization?
[A] World Bank
[B] Global Health Council
[C] World Health Organization (WHO)
[D] United Nations Children’s Emergency Fund (UNICEF)
[B] Global Health Council
[C] World Health Organization (WHO)
[D] United Nations Children’s Emergency Fund (UNICEF)
Correct Answer: C [World Health Organization (WHO)]
Notes:
A recent study by the Global Antibiotic Research and Development Partnership (GARDP) showed that many multidrug-resistant infections in low- and middle-income countries, including India, are not being treated properly due to lack of access. GARDP is a not-for-profit organization that creates new antibiotic treatments for drug-resistant bacterial infections and ensures they reach people in need. It focuses on public health by developing antibiotics to fight the current antimicrobial resistance (AMR) crisis and protect future generations. GARDP was founded by the World Health Organization (WHO) and Drugs for Neglected Diseases initiative (DNDi) under the Global Action Plan on AMR in 2015.
A recent study by the Global Antibiotic Research and Development Partnership (GARDP) showed that many multidrug-resistant infections in low- and middle-income countries, including India, are not being treated properly due to lack of access. GARDP is a not-for-profit organization that creates new antibiotic treatments for drug-resistant bacterial infections and ensures they reach people in need. It focuses on public health by developing antibiotics to fight the current antimicrobial resistance (AMR) crisis and protect future generations. GARDP was founded by the World Health Organization (WHO) and Drugs for Neglected Diseases initiative (DNDi) under the Global Action Plan on AMR in 2015.
65. What kind of disease is MASH (Metabolic Dysfunction-Associated Steatohepatitis) that was recently seen in news?
[A] A genetic brain disorder
[B] An autoimmune skin condition
[C] A serious form of fatty liver disease
[D] A bacterial lung infection
[B] An autoimmune skin condition
[C] A serious form of fatty liver disease
[D] A bacterial lung infection
Correct Answer: C [A serious form of fatty liver disease]
Notes:
A recent study in the New England Journal of Medicine found that a weekly dose of semaglutide shows strong results in treating Metabolic Dysfunction-Associated Steatohepatitis (MASH). Semaglutide is a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, first developed to treat Type 2 diabetes. It is the main ingredient in medicines like Ozempic, used for diabetes, and Wegovy, used for weight loss. MASH is a severe type of fatty liver disease caused by metabolic problems and not by alcohol. It involves fat buildup, inflammation, and liver scarring, and is linked to obesity, diabetes, and overnutrition. If not treated, MASH can lead to cirrhosis or liver failure.
A recent study in the New England Journal of Medicine found that a weekly dose of semaglutide shows strong results in treating Metabolic Dysfunction-Associated Steatohepatitis (MASH). Semaglutide is a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, first developed to treat Type 2 diabetes. It is the main ingredient in medicines like Ozempic, used for diabetes, and Wegovy, used for weight loss. MASH is a severe type of fatty liver disease caused by metabolic problems and not by alcohol. It involves fat buildup, inflammation, and liver scarring, and is linked to obesity, diabetes, and overnutrition. If not treated, MASH can lead to cirrhosis or liver failure.
66. Which organization developed the India’s High-Altitude Platform (HAP) prototype, a solar-powered, unmanned aircraft?
[A] National Aerospace Laboratories (NAL)
[B] Bharat Electronics Ltd (BEL)
[C] Indian Space Research Organisation (ISRO)
[D] Defence Research and Development Organisation (DRDO)
[B] Bharat Electronics Ltd (BEL)
[C] Indian Space Research Organisation (ISRO)
[D] Defence Research and Development Organisation (DRDO)
Correct Answer: A [National Aerospace Laboratories (NAL)]
Notes:
In a recent development, India’s High-Altitude Platform (HAP) prototype designed by National Aerospace Laboratories (NAL) successfully completed pre-monsoon flight tests with a certified autopilot system. A High-Altitude Platform (HAP) is an unmanned, solar-powered aircraft that flies in the stratosphere at 17 to 22 kilometers altitude. It serves as a middle layer between ground systems and satellites for continuous aerial services. It was developed by NAL, Bengaluru, under the Council of Scientific and Industrial Research (CSIR). The Aeronautical Test Range (ATR) at Chitradurga, Karnataka supported its development. It is designed for border patrolling, surveillance in remote areas, and civil-military use. It can also act as a relay for telecommunications and weather monitoring.
In a recent development, India’s High-Altitude Platform (HAP) prototype designed by National Aerospace Laboratories (NAL) successfully completed pre-monsoon flight tests with a certified autopilot system. A High-Altitude Platform (HAP) is an unmanned, solar-powered aircraft that flies in the stratosphere at 17 to 22 kilometers altitude. It serves as a middle layer between ground systems and satellites for continuous aerial services. It was developed by NAL, Bengaluru, under the Council of Scientific and Industrial Research (CSIR). The Aeronautical Test Range (ATR) at Chitradurga, Karnataka supported its development. It is designed for border patrolling, surveillance in remote areas, and civil-military use. It can also act as a relay for telecommunications and weather monitoring.
67. AI Matryoshka is a multi-layered artificial intelligence ecosystem launched by which organization?
[A] Google
[B] Meta
[C] Microsoft
[D] Amazon
[B] Meta
[C] Microsoft
[D] Amazon
Correct Answer: A [Google]
Notes:
At the I/O Developers Conference 2025, Google launched its AI-first restructuring strategy called AI Matryoshka. AI Matryoshka is a multi-layered artificial intelligence ecosystem where Google’s core AI acts like the central brain, similar to a Matryoshka doll. It is built around Gemini 2.5 models and aims to change how users, developers, and enterprises interact with technology. This system powers everything from Application Programming Interfaces (APIs) to user-facing apps. The goal is to deeply embed AI across all Google platforms and create smart, autonomous systems that respond in real time.
At the I/O Developers Conference 2025, Google launched its AI-first restructuring strategy called AI Matryoshka. AI Matryoshka is a multi-layered artificial intelligence ecosystem where Google’s core AI acts like the central brain, similar to a Matryoshka doll. It is built around Gemini 2.5 models and aims to change how users, developers, and enterprises interact with technology. This system powers everything from Application Programming Interfaces (APIs) to user-facing apps. The goal is to deeply embed AI across all Google platforms and create smart, autonomous systems that respond in real time.
68. What is Lysosomal Storage Disorder (LSD) that was recently seen in news?
[A] Bacterial infections of the liver
[B] Autoimmune disorders affecting the skin
[C] Rare genetic conditions causing toxic buildup in cells
[D] Hormonal imbalances affecting metabolism
[B] Autoimmune disorders affecting the skin
[C] Rare genetic conditions causing toxic buildup in cells
[D] Hormonal imbalances affecting metabolism
Correct Answer: C [Rare genetic conditions causing toxic buildup in cells]
Notes:
Recently, despite the launch of the National Policy for Rare Diseases (NPRD) in 2021 and a financial aid programme, over 300 patients, mostly children with Lysosomal Storage Disorders (LSDs), are not receiving proper medical treatment. LSDs are rare genetic disorders where harmful substances build up inside cells due to enzyme deficiencies. They are caused by mutations in the genes that produce lysosomal enzymes, which help break down waste in cells. These diseases can severely affect organs and quality of life.
Recently, despite the launch of the National Policy for Rare Diseases (NPRD) in 2021 and a financial aid programme, over 300 patients, mostly children with Lysosomal Storage Disorders (LSDs), are not receiving proper medical treatment. LSDs are rare genetic disorders where harmful substances build up inside cells due to enzyme deficiencies. They are caused by mutations in the genes that produce lysosomal enzymes, which help break down waste in cells. These diseases can severely affect organs and quality of life.
69. What is the name of India’s first agentic AI system developed by Krutrim start up?
[A] Mitra
[B] Sanchita
[C] Vaani
[D] Kruti
[B] Sanchita
[C] Vaani
[D] Kruti
Correct Answer: D [Kruti]
Notes:
Recently, India’s first agentic Artificial Intelligence (AI) named Kruti was launched by the startup Krutrim. It is a next-generation Generative AI (GenAI) tool that goes beyond just providing information. Kruti can act independently to manage complex tasks, make decisions, and solve problems for users and organizations. It uses advanced reasoning and step-by-step planning to handle multi-layered challenges without constant human input. It processes large amounts of data from various sources to create strategies and complete tasks on its own.
Recently, India’s first agentic Artificial Intelligence (AI) named Kruti was launched by the startup Krutrim. It is a next-generation Generative AI (GenAI) tool that goes beyond just providing information. Kruti can act independently to manage complex tasks, make decisions, and solve problems for users and organizations. It uses advanced reasoning and step-by-step planning to handle multi-layered challenges without constant human input. It processes large amounts of data from various sources to create strategies and complete tasks on its own.
70. Which country has launched the Zhangheng 1B satellite to strengthen early warning systems for natural disasters?
[A] South Korea
[B] Japan
[C] China
[D] Vietnam
[B] Japan
[C] China
[D] Vietnam
Correct Answer: C [China]
Notes:
China has launched the Zhangheng 1B satellite to strengthen early warning systems for natural disasters by monitoring Earth’s electromagnetic environment. It was launched aboard a Long March 2D rocket from the Jiuquan Satellite Launch Center in the Gobi Desert. Developed in partnership with Italy under a 2019 cooperation agreement, the satellite entered orbit as planned. Zhangheng 1B is China’s first satellite focused on studying geophysical fields from space and will work with Zhangheng 1A launched in 2018. It carries nine instruments, including an electric field detector and a high-energy particle sensor built by Italy.
China has launched the Zhangheng 1B satellite to strengthen early warning systems for natural disasters by monitoring Earth’s electromagnetic environment. It was launched aboard a Long March 2D rocket from the Jiuquan Satellite Launch Center in the Gobi Desert. Developed in partnership with Italy under a 2019 cooperation agreement, the satellite entered orbit as planned. Zhangheng 1B is China’s first satellite focused on studying geophysical fields from space and will work with Zhangheng 1A launched in 2018. It carries nine instruments, including an electric field detector and a high-energy particle sensor built by Italy.