Science & Technology Current Affairs MCQs

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In a historic milestone, Prime Minister Narendra Modi unveiled NexCAR19, India’s first indigenous CAR-T Cell Therapy, at the Emerging Science, Technology & Innovation Conclave (ESTIC) 2025 in Delhi. It is developed by ImmunoACT, an IIT Bombay spin-off. It is supported by the Department of Biotechnology (DBT) and Biotechnology Industry Research Assistance Council (BIRAC). NexCAR19 is the world’s first humanised CAR-T therapy, truly “Made in India, for the world.” CAR-T Cell Therapy is an immunotherapy that reprograms a patient’s immune cells to fight blood cancers like Acute Lymphocytic Leukemia (ALL).

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On November 5, 2025, the Government of Maharashtra became the first Indian state to sign a Letter of Intent (LoI) with Starlink Satellite Communications Pvt. Ltd., a SpaceX subsidiary, to provide satellite-based internet. The partnership aims to deliver high-speed internet to remote districts like Gadchiroli, Nandurbar, Washim, and Dharashiv in Maharashtra. Satellite terminals will be installed in schools, health centres, disaster control rooms, and forest and coastal outposts, extending connectivity to ports, ferries, and coastal police networks. The initiative supports Digital Maharashtra and aligns with Digital India to connect terrain- or cost-challenged regions.

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A global review has identified 57 new living species of foraminifera. Foraminifera, or forams, are single-celled marine organisms found in oceans, coasts, and estuaries. Most have shells and are either planktonic (float in water) or benthic (live on sea floor). They are generally under 500 microns in size, though some tropical species reach 20 cm. Their name comes from foramen (Latin for window), with holes in shells for pseudopodia to gather food. They eat detritus, diatoms, bacteria, algae, and tiny animals like copepods. Shells are made of calcium carbonate (calcareous) or sand grains (agglutinate) with one or multiple coiled chambers.

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Recently, researchers from the Central Marine Fisheries Research Institute (CMFRI), Kochi discovered a new deep-sea squid species in the Arabian Sea and named it Taningia silasii (Indian octopus squid). The species was found at a depth of nearly 390 metres off the Kollam coast. It belongs to the family Octopoteuthidae. It is only the second formally recognised species in the Taningia genus. The first species in this genus was Taningia danae, earlier found in the Atlantic Ocean.

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Skyroot Aerospace inaugurated its Infinity Campus in Hyderabad and virtually unveiled Vikram-I, India’s first private commercial orbital rocket. Vikram-I is capable of placing satellites into Earth orbit. This launch marks a major milestone for India’s growing private space sector. The private space sector in India was opened to entrepreneurs three years ago. The development highlights rising startup participation in advanced space technology. It reflects India’s shift toward innovation-driven and private-led space missions.

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Telangana’s 1 Bio, India’s first single-use bioprocess design and scale-up facility, was inaugurated at Genome Valley, Hyderabad. It was created to solve the lack of affordable bioprocess scale-up infrastructure despite Telangana’s strong biotech talent. The facility supports start-ups and big companies with end-to-end process development and pilot validation. It was developed by the Government of Telangana, Telangana Lifesciences, Department of Biotechnology (DBT), Government of India, and Telangana Industrial Infrastructure Corporation (TGIIC). It has 500-litre bioreactors, advanced processing systems, and analytical labs.

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The National Human Rights Commission (NHRC) reported that 97 central and state laws still have provisions discriminating against persons affected by leprosy. Leprosy (Hansen’s disease) is a chronic bacterial infection caused by bacteria Mycobacterium leprae affecting skin, peripheral nerves, and eyes, which can cause permanent disabilities if untreated. The bacteria spread through droplets from the nose and mouth during close, frequent contact with untreated cases. India’s prevalence rate decreased from 57.2 per 10,000 in 1981 to 0.57 per 10,000 in 2025, achieving national elimination status in 2005.

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Bluetongue Virus (BTV) has recently been detected in more suspected cases in Northern Ireland, raising concerns about livestock health. Bluetongue is a severe haemorrhagic disease that affects animals and is infectious, but it is non-contagious and spreads only through insect vectors. The virus mainly infects domestic ruminants such as cattle, sheep, and goats, as well as wild animals like buffalo, deer, antelope, and camels, with sheep being the most severely affected. It spreads primarily through the bites of infected Culicoides midges, which are tiny blood-feeding insects commonly found on farms. There is no effective treatment for bluetongue, but vaccines are available for certain strains and are used in Africa, Asia, and parts of Europe.

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Scientists at the Bose Institute, Kolkata have developed GlowCas9, a CRISPR protein that glows during gene editing. It is a bioluminescent Cas9, created by fusing Cas9 with a split nano-luciferase enzyme from deep-sea shrimp proteins. GlowCas9 is highly stable, retaining structure and activity even at higher temperatures. When Cas9 folds correctly, the luciferase pieces reconnect and produce light, enabling real-time, non-harmful tracking of gene editing in cells, tissues, and plant leaves. It improves the precision of Homology-Directed Repair (HDR), a key DNA repair process for genetic diseases like sickle cell anaemia and muscular dystrophy. GlowCas9 advances theratracking, the visual monitoring of molecular gene therapy in action.

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Researchers at the Indian Institute of Technology Delhi have developed an ingestible device that can directly sample bacteria from the small intestine. The innovation helps overcome limitations of current methods like endoscopy or stool analysis, which do not accurately reflect upper gut conditions. The pill-sized device remains closed in the stomach and opens only in the intestine to collect bacterial samples, then reseals safely. It uses an enteric-coated gelatin cap that dissolves at intestinal pH, allowing fluid and microbes to enter sampling chambers. The study was conducted in collaboration with the All India Institute of Medical Sciences Delhi and funded by the Indian Council of Medical Research.