Science & Technology Current Affairs MCQs

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In November 2025, the World Health Organization (WHO) confirmed an outbreak of Rift Valley Fever (RVF) in Mauritania and Senegal, Western Africa. Rift Valley Fever is caused by a Phlebovirus from the Phenuiviridae family. It mainly affects animals such as sheep, goats, cattle, and camels. Humans get infected through contact with infected animals or mosquito bites. It does not spread from person to person. The disease was first identified in Kenya’s Rift Valley in the 1930s. It later spread across sub-Saharan Africa, Egypt, Saudi Arabia, and Yemen.

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India’s first indigenous CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-based gene therapy for Sickle Cell Disease (SCD), named BIRSA 101, was recently launched by the Union Minister of State (Independent Charge) for Science & Technology. It is developed by CSIR (Council of Scientific and Industrial Research) – Institute of Genomics and Integrative Biology (IGIB). BIRSA 101 uses CRISPR-Cas9 gene-editing technology to precisely correct the genetic mutation causing SCD. The therapy is administered as a one-time infusion, after which the body produces normal red blood cells instead of sickle-shaped ones.

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Telangana’s 1 Bio, India’s first single-use bioprocess design and scale-up facility, was inaugurated at Genome Valley, Hyderabad. It was created to solve the lack of affordable bioprocess scale-up infrastructure despite Telangana’s strong biotech talent. The facility supports start-ups and big companies with end-to-end process development and pilot validation. It was developed by the Government of Telangana, Telangana Lifesciences, Department of Biotechnology (DBT), Government of India, and Telangana Industrial Infrastructure Corporation (TGIIC). It has 500-litre bioreactors, advanced processing systems, and analytical labs.

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Samudrayaan is India’s first manned deep-ocean submersible mission to reach 6,000 metres depth. Testing is delayed due to late supply of syntactic foam from France, now expected by year-end after testing in Norway. The project is led by National Institute of Ocean Technology under the Ministry of Earth Sciences. A steel model has been tested up to 100 metres; a 500-metre trial is planned by April next year. The final titanium hull, built by Indian Space Research Organisation, will be tested in Russia. The mission will carry three crew members to collect seabed soil and rocks for future deep-sea mining.

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Union Minister of State (Independent Charge) for Science & Technology, Dr. Jitendra Singh, launched Hansa-3(NG), first indigenous all-composite two-seater trainer aircraft for Private Pilot License (PPL) and Commercial Pilot License (CPL) training at CSIR–National Aerospace Laboratories (NAL), Bengaluru. Hansa-3(NG) reduces foreign dependence and boosts aviation entrepreneurship. The aircraft will help flying clubs meet India’s growing demand for trained pilots.

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The World Health Organization has issued the first global guidelines on Glucagon-Like Peptide-1 (GLP-1) drugs for weight loss. GLP-1 receptor agonists are synthetic medicines used to treat adult obesity and type-2 diabetes. These drugs are mainly injectable, while oral versions are under development. Leading examples are Semaglutide and Tirzepatide, now available in India. They increase insulin, reduce glucagon, slow stomach emptying, and suppress appetite, helping control blood sugar and body weight.

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Meta is reportedly in advanced talks with Google to use its Tensor Processing Units (TPUs). A Tensor Processing Unit (TPU) is a special chip made to speed up Artificial Intelligence (AI) and Machine Learning (ML) tasks. TPUs, developed by Google in 2016, power applications like Google Search, Translate and Photos. They are now widely used in data centres and cloud computing for large AI workloads. TPUs work on tensor computations, which are multi-dimensional data arrays used in deep learning. They offer massive parallel processing, low power use and specialised circuits for AI tasks.

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A new study warns that heavy use of artemisinin and favourable conditions can create new hotspots of drug resistance, with resistance markers slowly rising in parts of Africa. Artemisinin is an antimalarial drug obtained from the sweet wormwood plant called Artemisia annua. It was discovered in the 1970s and became a major breakthrough when malaria parasites developed resistance to older drugs like chloroquine. It is effective against all malaria-causing parasites of the Plasmodium genus, mainly during the blood stage. Artemisinin quickly reduces parasites but stays in the body for a short time, so it is combined with other drugs. The World Health Organization recommends artemisinin-based combination therapies as the standard treatment for Plasmodium falciparum malaria.

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Kavach is an indigenously developed Automatic Train Protection (ATP) system designed to improve railway operational safety across the Indian Railways network. It was developed by the Research Design and Standards Organisation (RDSO) of Indian Railways. As of December 2025, the system has been commissioned on over 2,000 km of railway routes, with 7,129 km of Optical Fibre Cable (OFC) laid, 860 telecom towers installed, 767 stations connected, 3,413 km of trackside equipment deployed, and 4,154 locomotives fitted with Kavach. About 40,000 technicians and operators have been trained, reflecting the scale of operational readiness.

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Researchers from Bose Institute, Kolkata, in collaboration with L V Prasad Eye Institute, Hyderabad, have developed a peptide therapy for fungal keratitis, a severe infection of the cornea. They designed a 15-residue peptide, SA-XV, derived from the host-defense peptide S100A12, previously known to inhibit fungal growth. SA-XV acts by interacting with fungal cell walls and membranes, translocating into the cytoplasm, binding nuclear DNA to halt the cell cycle, and targeting mitochondria to induce apoptosis.