Men are more vulnerable to COVID-19 than women: How and Why?

Initially there was a hypothesis that men might be more vulnerable to COVID-19 virus than women. However, the hypothesis has now been proved by a research published in the European Heart Journal.


The ACE2 enzyme in the human body is the key factor that enables the COVID-19 to infect human cells. The study has found out that levels of ACE2 enzymes are more in men than in women.

What is ACE2 enzyme?

The angiotensin Converting Enzyme 2 lies in the outer surface of cells of lungs, heart, kidneys. The primary function of the enzyme is to regulate the transport of amino acids (amino acids are formed from digestion of proteins).

The ACE2 enzymes act as main entry points for the COVID-19 virus. There are hypothetical studies that say that reducing level of ACE2 enzyme could be a successful treatment for COVID-19.

The ACE inhibiting drugs are used to cure heart diseases. They also help in reducing blood pressure.


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