61. PathGennie is a novel computational framework developed by which institute?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Indian Institute of Technology (IIT), Bombay
[C] S. N. Bose National Centre for Basic Sciences, Kolkata
[D] National Chemical Laboratory (NCL), Pune
Show Answer
Correct Answer: C [S. N. Bose National Centre for Basic Sciences, Kolkata]
Notes:
PathGennie is a novel computational framework developed by scientists at S. N. Bose National Centre for Basic Sciences, Kolkata (DST autonomous institute). Published in the Journal of Chemical Theory and Computation, it accelerates simulation of rare molecular events for computer-aided drug discovery (CADD). It focuses on predicting drug unbinding from protein targets without artificial biases used in classical methods. PathGennie uses direction-guided adaptive sampling, launching many ultrashort unbiased MD trajectories and extending only productive ones (“survival of the fittest”).
62. What kind of disease is ‘Ulcerative colitis’ that was recently seen in news?
[A] Infectious disease
[B] Metabolic disorder
[C] Genetic blood disorder
[D] Chronic inflammatory bowel disease
Show Answer
Correct Answer: D [Chronic inflammatory bowel disease]
Notes:
A new study suggests ulcerative colitis may be triggered when a normally hidden protective layer of immune cells beneath the gut lining becomes thinner. Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) affecting the colon and rectum. It causes long-term inflammation and ulcers in the inner lining of the large intestine. Ulcerative colitis (UC) is an immune-mediated condition with cycles of flare-ups and remission.
63. India has inaugurated the world’s second National Environmental Standard Laboratory (NESL) in which city?
[A] Bengaluru
[B] New Delhi
[C] Chennai
[D] Hyderabad
Show Answer
Correct Answer: B [New Delhi]
Notes:
India inaugurated the world’s second National Environmental Standard Laboratory (NESL) and the world’s fifth National Primary Standard Facility for Solar Cell Calibration at CSIR–National Physical Laboratory (NPL), New Delhi. NESL will provide India-specific calibration and certification of air pollution monitoring systems, supporting regulatory bodies, industries, and startups, and improving policy enforcement under programmes like the National Clean Air Programme (NCAP).
64. What is ‘W Ursae Majoris (W UMa)’ that was recently seen in news?
[A] Binary Star
[B] Asteroid
[C] Exoplanet
[D] None of the Above
Show Answer
Correct Answer: A [Binary Star]
Notes:
Astronomers from Aryabhatta Research Institute of Observational Sciences studied the W Ursae Majoris (W UMa) star. They used data from Devasthal Fast Optical Telescope and NASA’s Transiting Exoplanet Survey Satellite (TESS). W UMa is a low-mass contact binary and an eclipsing binary variable star. The two stars share a single outer atmosphere and orbit each other. W UMa stars show light curves with nearly equal minima and continuous brightness variation. Studying W UMa helps determine stellar masses, radii, and temperatures, aiding understanding of stellar evolution.
65. Which telescope of NASA recently discovered a new astronomical object named Cloud-9?
[A] Spitzer Space Telescope
[B] Roman Space Telescope
[C] Hubble Space Telescope
[D] James Webb Space Telescope
Show Answer
Correct Answer: C [Hubble Space Telescope]
Notes:
NASA’s Hubble Space Telescope discovered a new astronomical object named Cloud-9. Cloud-9 is a starless, gas-rich, dark-matter-dominated cloud, classified as a Reionization-Limited H I Cloud (RELHIC). It is located 14 million light-years from Earth, near the spiral galaxy Messier 94 (M94). The cloud is made of neutral hydrogen (H I) spanning about 4,900 light-years, with a mass approx 1 million times the Sun. Cloud-9’s dark matter mass is estimated at 5 billion solar masses. It is a relic of early galaxy formation, a “failed galaxy” that did not form stars.
66. Artemis II mission is associated with which space agency?
[A] European Space Agency (ESA)
[B] Indian Space Research Organisation (ISRO)
[C] National Aeronautics and Space Administration (NASA)
[D] Russian Space Agency (Roscosmos)
Show Answer
Correct Answer: C [National Aeronautics and Space Administration (NASA)]
Notes:
Artemis II is the first crewed mission of NASA’s Artemis programme and will mark humanity’s return to the Moon’s vicinity for the first time since 1972. The 10-day mission will test the Space Launch System (SLS) rocket and the Orion spacecraft to verify life-support, navigation, and safety systems for future lunar missions. On January 9, NASA announced that Artemis II had entered its final preparation phase. The fully assembled rocket is expected to be rolled out to Launch Pad 39B at the Kennedy Space Centre in mid-January for final testing.
67. The CSIR Integrated Skill Initiative is a flagship programme of which institution?
[A] Department of Science and Technology (DST)
[B] Council of Scientific and Industrial Research (CSIR)
[C] Ministry of Skill Development and Entrepreneurship
[D] NITI Aayog
Show Answer
Correct Answer: B [Council of Scientific and Industrial Research (CSIR)]
Notes:
Recently, the CSIR Integrated Skill Initiative trained over 1.90 lakh individuals through more than 5,200 skill-based programmes. It is a flagship national programme of the Council of Scientific and Industrial Research (CSIR). It aims to bridge the gap between scientific research, industry needs, and employable skills. The initiative integrates skill development with science and technology using CSIR’s research infrastructure. It offers inclusive access to students, researchers, professionals, school dropouts, ITI diploma holders, farmers, and rural communities.
68. Guillain-Barré Syndrome (GBS), that was recently seen in news, is classified as which type of disease?
[A] Autoimmune neurological disorder
[B] Respiratory disease
[C] Cardiovascular disease
[D] Infectious bacterial disease
Show Answer
Correct Answer: A [Autoimmune neurological disorder]
Notes:
A Guillain-Barré Syndrome (GBS) outbreak has been reported in Neemuch district of Madhya Pradesh, with two deaths in Manasa town. Guillain-Barré Syndrome is a rare neurological disorder in which the body’s immune system attacks the peripheral nervous system. The peripheral nervous system is the network of nerves outside the brain and spinal cord that controls movement, pain, and sensations. Since the immune system causes the damage, it is an autoimmune disease, also called acute inflammatory demyelinating polyradiculoneuropathy.
69. Which institution developed a solar-powered energy storage device that can capture and store energy in a single unit?
[A] Indian Institute of Science (IISc), Bengaluru
[B] Bhabha Atomic Research Centre (BARC), Mumbai
[C] Centre for Nano and Soft Matter Sciences (CNSMS), Bengaluru
[D] Indian Institute of Technology, Delhi
Show Answer
Correct Answer: C [Centre for Nano and Soft Matter Sciences (CNSMS), Bengaluru]
Notes:
Indian scientists from Centre for Nano and Soft Matter Sciences, Bengaluru under Department of Science and Technology (DST) developed a solar-powered energy storage device that captures and stores energy in a single unit. The device is known as a photo-rechargeable supercapacitor. Unlike conventional systems, it combines energy harvesting and storage, reducing cost, energy loss, system complexity, and footprint. It enables portable, wearable, off-grid applications, reduces reliance on fossil fuels and conventional batteries, and works in remote areas.
70. Indian National Centre for Ocean Information Services (INCOIS) was established under which ministry?
[A] Ministry of Science and Technology
[B] Ministry of Earth Sciences
[C] Ministry of Electronics and Information Technology
[D] Ministry of Environment, Forest and Climate Change
Show Answer
Correct Answer: B [Ministry of Earth Sciences]
Notes:
The Indian National Centre for Ocean Information Services (INCOIS) will launch three new ocean services: Jellyfish Artificial Intelligence Information Platform (JellyAIIP), SAMUDRA 2.0 Mobile Application, and Seamless Information Visualization and Analysis System (SIVAS) along with a new logo. It was established as an autonomous body under the Ministry of Earth Sciences (MoES) and is located in Hyderabad, Telangana. It provides ocean information and advisory services through continuous ocean observations and focused research. It runs the Indian Tsunami Early Warning Centre (ITEWC), issuing tsunami alerts within 10 minutes for India and 28 Indian Ocean countries.