1. What is ‘Leber congenital amaurosis’, recently seen in news?
[A] A neurological disorder
[B] A rare genetic eye disorder
[C] A type of skin condition
[D] A cardiovascular disease
Show Answer
Correct Answer: B [A rare genetic eye disorder ]
Notes:
Researchers utilized CRISPR-Cas9 to restore vision in individuals with Leber congenital amaurosis (LCA), a rare genetic eye disorder causing blindness from birth. LCA affects 1 in 40,000 people, impairing light-sensitive cells due to a mutation in the CEP290 gene. The “BRILLIANCE” trial administered a single dose of CRISPR therapy, EDIT-101, which corrected the mutation, enabling proper function of the CEP290 protein, thus restoring vision by allowing the retina to perceive light.
2. What is ‘FLiRT’, recently seen in news?
[A] Nuclear ballistic submarine
[B] Malicious software
[C] An underwater research station
[D] New variant of COVID19
Show Answer
Correct Answer: D [New variant of COVID19]
Notes:
FLiRT, a new variant of COVID-19, has emerged as the dominant strain in the United States. It belongs to the Omicron JN.1 lineage and features two mutations, KP 1.1 and KP.2. Rapidly spreading, FLiRT exhibits diverse symptoms including sore throat, cough, fatigue, nasal congestion, headache, muscle aches, fever, and gastric issues. Continuous monitoring and appropriate public health measures are essential to address its rapid transmission.
3. What is ‘55 Cancri e’, recently seen in news?
[A] Invasive weed
[B] Super-Earth
[C] Ancient irrigation technique
[D] Submarine
Show Answer
Correct Answer: B [Super-Earth]
Notes:
Scientists have found a super-Earth, 55 Cancri e, near our solar system. It’s twice Earth’s size with a thick atmosphere rich in carbon dioxide and monoxide. Orbiting its star, Copernicus, at a close distance, it completes an orbit every 18 hours. Positioned 41 light years away, it faces perpetual day and night. A light-year equals nearly six trillion miles, illustrating the vast gap between Earth and this exoplanet.
4. Recently, which Indian created history by becoming the first Indian space tourist?
[A] Ashutosh Sharma
[B] Gopi Thotakura
[C] Akhilesh Gupta
[D] Balram Bhargava
Show Answer
Correct Answer: B [Gopi Thotakura ]
Notes:
Gopi Thotakura, an Indian expatriate, became the first Indian space tourist and the second Indian in space on Blue Origin’s NS-25 mission. The mission, New Shepard’s seventh human spaceflight, included six crew members, among them Gopi Thotakura. The crew also featured historical figure Ed Dwight, the first black astronaut candidate selected by President Kennedy. New Shepard has now flown 37 people into space, marking another milestone in space tourism.
5. What is ‘Pig butchering scam’, recently seen in news?
[A] It is a type of scam in which victims are asked to invest in pig farms
[B] It is a type of online investment fraud by creating fake online personas
[C] It refers to actual butchering of pigs for profit
[D] It is related to a cooking technique used in certain cuisines
Show Answer
Correct Answer: B [It is a type of online investment fraud by creating fake online personas]
Notes:
Pig Butchering Scams, also known as “sha zhu pan” scams, are rising globally, notably in India. Scammers create fake online personas to lure victims into fraudulent investment schemes. They build trust over time, dubbed “fattening the pig,” before stealing money. Initially contacting targets through social media or dating apps, scammers deceive victims into cryptocurrency trading via fake apps. Withdrawal attempts are met with excuses or hefty fees, making fund retrieval challenging due to blockchain transactions’ nature.
6. Recently, how many nations have signed the Zero Debris Charter at the ESA/EU Space Council?
[A] 11
[B] 12
[C] 13
[D] 14
Show Answer
Correct Answer: B [12]
Notes:
Twelve nations signed the Zero Debris Charter at the ESA/EU Space Council, committing to sustainable human activities in Earth orbit. The European Space Agency (ESA) initiated the Charter in November 2023. It aims to eliminate space debris by 2030 through ambitious technical targets and global cooperation. Although non-binding, it sets key goals like a debris generation probability below 1 in 1,000 per object and 99% post-mission disposal success.
7. Which institute recently launched the ‘Electric Tiller’?
[A] CSIR-Central Mechanical Engineering Research
[B] CSIR-Central Leather Research Institute
[C] CSIR-Central Institute of Mining and Fuel Research
[D] CSIR-Advanced Materials and Processes Research
Show Answer
Correct Answer: A [CSIR-Central Mechanical Engineering Research]
Notes:
CSIR-Central Mechanical Engineering Research launched an Electric Tiller for small farmers, prioritizing user comfort and eco-sustainability. Features include enhanced torque, electronic controls, and versatile charging options like AC and Solar DC. It produces zero exhaust emissions, supporting India’s commitment to eco-friendly farming. Compatible with various attachments, it minimizes operator fatigue, boosts productivity, and has the potential to reduce operational costs by up to 85%. Tilling improves soil quality and promotes healthy crop growth.
8. Recently, Tata Consultancy Services has entered a strategic partnership with which institute to develop India’s first Quantum Diamond Microchip Imager?
[A] IIT Madras
[B] IIT Delhi
[C] IIT Bombay
[D] IIT Roorkee
Show Answer
Correct Answer: C [IIT Bombay]
Notes:
The Indian Institute of Technology Bombay (IIT-Bombay) partnered with Tata Consultancy Services (TCS) to develop India’s first Quantum Diamond Microchip Imager, aligned with the National Quantum Mission. This imager uses Nitrogen-Vacancy (NV) centers in diamonds to detect and characterize anomalies in semiconductor chips. It enables non-invasive, non-destructive magnetic field imaging of semiconductor chips, similar to an MRI in hospitals.
9. What is ‘Neo’, recently seen in news?
[A] a novel protein
[B] Asteroid
[C] Invasive weed
[D] Exoplanet
Show Answer
Correct Answer: A [a novel protein]
Notes:
Recent research identified a novel protein, “Neo,” crucial in bacterial defense against bacteriophages. Discovered by Stephen Tang and Samuel Sternberg in Klebsiella pneumoniae, Neo is part of the DRT-2 system. It involves rolling-circle reverse transcription of non-coding RNA, producing double-stranded cDNA upon phage infection. This cDNA generates mRNAs encoding the Neo protein, which induces bacterial cell dormancy, protecting the population from phage spread.
10. What is Huntington’s Disease (HD), recently seen in news?
[A] A viral infection that affects the liver
[B] An inherited disorder that causes nerve cells in parts of the brain to gradually break down and die
[C] A bacterial infection that affects the lungs
[D] A nutritional deficiency that affects the bones
Show Answer
Correct Answer: B [An inherited disorder that causes nerve cells in parts of the brain to gradually break down and die]
Notes:
Scientists in the UK have developed non-invasive techniques and novel analysis methods to track disease progression and evaluate treatments for Huntington’s disease (HD). HD, an inherited disorder caused by a mutation in the HTT gene, leads to the breakdown of nerve cells in the brain, affecting movement, cognition, and psychiatric health. It manifests primarily in adulthood but can also begin in childhood. Increased genetic repetitions worsen the disease’s severity.