LZTFL1
The LZTFL1 is Leucine zipper transcription factor like 1. It is a human gene.
About LZTFL1
- The gene regulates protein trafficking. Protein trafficking means transporting proteins throughout the cells.
- It is a tumor suppressor gene.
- The mutations in LZTFL1 causes Bardet Biedl syndrome.
- The gene is located in chromosome 3 in human beings.
- The LZTFL1 was inherited by the homo sapiens from the Neanderthals.
LZTFL1 relation with COVID-19
In November 2021, researchers found that the LZTFL1 gene doubles the risk of respiratory failures in COVID-19. This gene is found in more than 60% of South Asians. On the other hand, only 15% of Europeans and 2% of Africans and Caribbeans carry this gene. This explains that the Asians are more susceptible to COVID-19 virus. The researchers found that the gene prevents the cells lining the lungs and the airway from responding to COVID-19 virus. Thus, the risk of respiratory failure increases. The gene affects only the responses of lungs and not its immune system.
Originally written on
November 8, 2021
and last modified on
February 20, 2022.
