Dare2eraD TB Research

A Data-Driven Research named “Dare2eraD TB” has been launched by the Department of Biotechnology, Ministry of Science and Technology to eradicate TB. This initiative was launched on 24th March on the occasion of World TB Day.

About the initiative

The Dare2eraD TB is comprised of key initiatives which are:

  • Indian Tuberculosis Genomic Surveillance Consortium (InTGS).
  • Indian TB Knowledge Hub- Webinar Series (InTBK Hub).
  • Host Directed therapies against TB.
  • Developing of evidence-based regimen so that extra-pulmonary Tuberculosis can be treated.

About InTGS

The InTGS has been proposed on similar lines to the Indian SARS-CoV-2 Genomic Consortia

About InTBK Hub

This will be a Webinar series that began on World TB Day. It will create a connection between the industry and the academia to discuss various challenges and ideas will be exchanged. Innovations will also be carried forward among all the TB stakeholders.

About Whole Genome Sequencing

To fully understand Mycobacterium tuberculosis’s (Mtb) biological characteristics and the effect that occurs due to mutations on treatment, transmission, and severity of disease, it is necessary to analyse the organism’s genomic data as Whole Genome Sequencing (WGS) is continuously gaining traction as a molecular tool which is important for the surveillance of Tuberculosis.

WGS technology’s effective use will allow identification of the origin as well as drug resistance profile TB strains in patients across the nation. Doing this would help in facilitating treatment strategies for better TB transmission control.

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