One Health Priority Research Agenda on Antimicrobial Resistance

July 5, 2023

The release of the One Health Priority Research Agenda on Antimicrobial Resistance (AMR) by key organizations, including FAO, UNEP, WHO, and WOAH, signifies a significant step towards addressing the critical issue of AMR. This collaborative effort aims to optimize the health of people, animals, and ecosystems through a comprehensive approach known as One Health.  

The Global Research Agenda for AMR 

On June 22, 2023, the World Health Organization (WHO) launched a global research agenda for AMR in human health. This comprehensive agenda prioritizes 40 research topics, providing a roadmap for generating evidence to inform policies and interventions by 2030. By focusing on low- and middle-income countries (LMICs), this agenda aims to reduce the burden of AMR on a global scale. 

Cross-Cutting Themes 

The One Health Priority Research Agenda identifies three crucial cross-cutting themes: gender, vulnerable populations, and sustainability. Recognizing the interconnectedness of these factors with AMR, the agenda emphasizes the need for research that addresses these themes comprehensively. 

Pillars of the Research Agenda

  1. Transmission: The transmission pillar focuses on understanding the transmission, circulation, and spread of AMR across various sectors, including the environment, plants, animals, and humans. By identifying the drivers of transmission and the impact on different sectors, this pillar aims to develop strategies to mitigate AMR spread effectively. 
  1. Integrated Surveillance: The goal of the integrated surveillance pillar is to enhance technical understanding and information exchange among stakeholders involved in One Health. By harmonizing surveillance efforts and prioritizing LMICs, this pillar aims to improve the effectiveness and implementation of integrated surveillance systems for AMR. 
  1. Interventions: The interventions pillar concentrates on programs, practices, tools, and activities aimed at preventing, containing, or reducing the incidence, prevalence, and spread of AMR. It highlights the importance of utilizing existing vaccines and other One Health-related measures to effectively combat AMR. 
  1. Behavioral Insights and Change: Understanding human behavior and its impact on AMR development and spread is the key focus of this pillar. It aims to explore and address behavioral aspects across various groups and actors involved in combating AMR. Insights gained through this research will contribute to targeted interventions and behavioral change strategies. 
  1. Economics and Policy: The economics and policy pillar addresses investment and action required for AMR prevention and control from a One Health perspective. It examines the cost-effectiveness of AMR investments, financial sustainability, and long-term impacts. This pillar emphasizes the need for financial planning to support AMR-related initiatives effectively. 
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