Both 1 & 2
Anemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen- binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. Most commonly, people with anemia report feelings of weakness, or fatigue, general malaise and sometimes poor concentration.