Pedro Álvares Cabral
Two years later in September 1500, Pedro Álvares Cabral sailed to India, who had done a wonder by discovering Brazil on the way.
Pedro established the first Portuguese factory at Calicut.
He was able to make some advantageous treaties with the rulers of Cochin and Cannanore , but at Calicut, his venture precipitated matters with the Arabs. Matters worsened when Cabral notoriously captured several vessels at the port and massacred the crew; the locals and Arabs retaliated by burning down the factory and butchering several Portuguese.
This is known as Battle of Calicut in which Cabral was defeated by the Arabs and locals.
Cabral started on the return voyage on 16 January 1501. He arrived in Portugal with only 4 of 13 ships on 23 June 1501, defeated and humiliated.