The Mizoroki-Heck reaction is a cross-coupling reaction that typically involves the coupling of aryl halides with alkenes. It is primarily catalyzed by palladium (Pd) complexes. Palladium is favored due to its ability to facilitate the oxidative addition and reductive elimination steps essential for the reaction. Rhodium, while also a transition metal, is less commonly used for this specific reaction. The Mizoroki-Heck reaction is important in organic synthesis for forming carbon-carbon bonds and is widely utilized in pharmaceuticals and materials science.
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