Camp Hill virus, a henipavirus related to Nipah, has been detected in North America, raising outbreak concerns. Henipaviruses are zoonotic RNA viruses from the Paramyxoviridae family, naturally hosted by fruit bats (Pteropus species). They can cross species barriers, infecting mammals, including humans, causing severe respiratory illness and encephalitis. Transmission occurs through infected animals, contaminated food/water, and human-to-human contact. Symptoms range from fever and headache to severe encephalitis, seizures, and coma. Henipaviruses block the innate immune response, aiding viral replication. No vaccine or antiviral drug is available; treatment is only symptomatic.
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