Chronic exposure to which among the following minerals/ salts in groundwater may cause Black-Foot Disease?

Q. Chronic exposure to which among the following minerals/ salts in groundwater may cause Black-Foot Disease?
Answer: Arsenic
Notes: Arsenicosis or Black foot is caused by exposure over a period of time to Arsenic in drinking water. It may also be due to intake of arsenic via food or air. Kindly note that Itai-itai disease is caused by Cadmium poisoning.