Recently, IIT Roorkee developed a new drug candidate, Compound 3b, to fight deadly drug-resistant bacteria. It targets KPC-2-producing Klebsiella pneumoniae, a World Health Organization (WHO) top-priority superbug. Compound 3b is a β-lactamase inhibitor that stops bacterial enzymes from breaking down antibiotics. It works with the antibiotic Meropenem, restoring its effectiveness against resistant infections. Preclinical lab and animal tests showed major infection reduction in lungs and safety to human cells. It marks a major step against antimicrobial resistance and boosts India’s role in global biomedical research.
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