Answer: Bose Institute, Kolkata
Notes: Recently, scientists at Bose Institute, Kolkata, developed a modified CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) tool to help plants fight heat stress and bacterial infections, boosting smart and sustainable farming. Unlike traditional CRISPR which cuts DNA, the team used a modified version called dCas9 (dead Cas9), which does not cut DNA but works like a gene switch. This switch stays off until the plant is stressed, such as by high temperatures. The scientists used a part of a natural tomato protein called NACMTF3, specifically its TM (Transmembrane) domain, to control the switch. Under heat stress, the TM domain releases dCas9, allowing it to enter the nucleus and turn on defense genes. This method allows plants to respond only when needed, reducing energy use and improving resilience.
