In April 2006, Nature journal announced that the earliest evidence of drilling holes in human teeth while the person was still alive was found at the Mehrgarh neolithic site in Balochistan, Pakistan dating around 7,500 BCE to 9,000 BCE. Eleven drilled molar crowns were discovered here revealing the first known instance of proto-dentistry practiced anywhere in the world. This indicates advanced medical knowledge and skills amongst the early farming communities of Mehrgarh.
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