Q. Which institution has developed the LICONN technology to map brain cell connections using light microscopes?
Answer: Institute of Science and Technology Austria (ISTA)
Notes: Scientists recently developed a new technique called Light-microscopy-based Connectomics (LICONN) to map brain cell connections using light microscopes. LICONN was developed at the Institute of Science and Technology Austria (ISTA). It allows mapping of brain’s complex neural networks at the nanoscale and also identifies specific molecules in those connections. LICONN combines light microscopy with hydrogel expansion, fluorescent stains, artificial intelligence (AI), and analytical methods. Brain tissue is soaked in a special gel that expands it 16 times, making tiny structures visible under light microscopes. It is the first method after electron microscopy (EM) that can reconstruct all synaptic connections between neurons.

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