Integral membrane proteins Current Affairs, GK & News

Disarib

Disarib is a noble small molecule, designed and synthesised by Indian researchers, has shown promise in targeted killing of cancer cells. The molecule (Disarib) works by binding itself to a protein called BCL2, which suppresses the death of cancerous cells. While BCL2 protein is produced in excess in cancer cells, its expression is almost undetectable ..

Topics: Apoptosis • Bcl-2 • Bcl-xL • Biology • Branches of biology • Cancer cell • Cell biology • Cellular senescence • HRK • Immunology • Integral membrane proteins • Programmed cell death

2012 Chemistry Nobel for Lefkowitz, Kobilka

US scientists Robert Lefkowitz and Brian Kobilka win the 2012 Nobel Prize in chemistry for studies of an important family of protein receptors, called G-protein-coupled receptors. What are G-protein-coupled receptors? It is an important family of receptors found in human body cells which allow the cell to sense and respond to outside chemical signals like ..

Topics: Biology • Branches of biology • Brian Kobilka • Cell signaling • G protein • G protein-coupled receptors • Hormone • Integral membrane proteins • Protein families • Receptor • Signal transduction • Taste