The Indian scientists have explored the possibility of reaching out to cancer cells and triggering their natural programmed death. How does this approach work? The approach uses the combined effect of targeting and inducing a ‘stress’ inside the Endoplasmic Reticulum of tumour cells and administering a small amount of a drug. The laboratory tests on ..
Cell biology: GK, General Studies and Current Affairs
Dr. Chandrima Shaha is set to be the first woman president of the Indian National Science Academy (INSA). She is currently Professor of Eminence at the National Institute of Immunology (NII) of Delhi. As a biologist, Ms. Shaha has focussed on apoptosis (or programmed cell death). Her laboratory uses the uni-cellular leishmania parasite as a ..
Disarib is a noble small molecule, designed and synthesised by Indian researchers, has shown promise in targeted killing of cancer cells. The molecule (Disarib) works by binding itself to a protein called BCL2, which suppresses the death of cancerous cells. While BCL2 protein is produced in excess in cancer cells, its expression is almost undetectable ..
The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank and Richard Henderson for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution. It’s a method of simplifying and improving the imaging of biomolecules.