On the cellular level, the most important hazard due the use of persistent chemical DDT is that:
The plasma membrane is made up mostly of lipids (fats). Remember that DDT is fat soluble, and so it will dissolve easily into the plasma membrane. In order to get into the plasma membrane, the DDT must open up the membrane slightly to make room for itself. DDT, unfortunately, opens up the membrane a little too much and causes the cell to leak. On the other hand, DDT is soluble in lipids (fats). This means that once an animal ingests a little DDT, it will mix in with its fat. And as we all know, all organisms (including human beings) have a certain amount of residual fat in their bodies. Once DDT gets in there, it tends to stay.
This question is a part of GKToday's Integrated IAS General Studies Module